jam.iitm.ac.in Biotechnology Question Paper Sample : Indian Institute of Technology Madras
Name of the Organisation : Indian Institute of Technology Madras
Name of the Exam : JAM Exam
Document Type : Sample Question Paper
Name of the Subject : Biotechnology (BT)
Website : jam.iitm.ac.in
Download Sample Question Paper 2015 : https://www.pdfquestion.in/uploads/7704-BTQP2015.pdf
Download Sample Question Paper 2014 : https://www.pdfquestion.in/uploads/7704-BTQP2014.pdf
Download Sample Question Paper 2013 : https://www.pdfquestion.in/uploads/7704-BTQP2013.pdf
JAM Biotechnology Sample Questions
Download Question Paper of JAM Exam Biotechnology Sample Question Paper is now available in the official website of Indian Institute of Technology Madras.
Related : Indian Institute of Technology Madras Biological Sciences Question Paper Model : www.pdfquestion.in/7701.html
General Instructions
1. Total duration of the JAM 2015 examination is 180 minutes.
2. The clock will be set at the server. The countdown timer at the top right corner of screen will display the remaining time available for you to complete the examination. When the timer reaches zero, the examination will end by itself. You need not terminate the examination or submit your paper.
3. Any useful data required for your paper can be viewed by clicking on the Useful Data button that appears on the screen.
4. Use the scribble pad provided to you for any rough work. Submit the scribble pad at the end of the examination.
5. You are allowed to use only your own non-programmable calculator.
6. The Question Palette displayed on the right side of screen will show the status of each question using one of the following symbols
7. The Marked for Review status for a question simply indicates that you would like to look at that question again. If a question is ‘answered, but marked for review’, then the answer will be considered for evaluation unless the status is modified by the candidate.
Model Questions
Section – A :
Multiple Choice Questions : (Mcq) Q. 1 – Q.10 carry one mark each.
Q.1 Which one of the following most accurately describes the process of natural selection?
(A) Selection of one species over a competing species
(B) Selection of individuals that successfully defend themselves against enemies
(C) Selection of individuals that produce more than the average number of offspring
(D) Selection of individuals that are more attractive to the opposite sex
Q.2 Identify the statement that is TRUE of operons.
(A) Fine regulation of the expression of individual genes are made possible by operons
(B) Only genes involved in carbohydrate metabolism are present in operons
(C) Feedback inhibition of the biosynthesis of multiple enzymes by a single small molecule is madepossible by operons
(D) In the case of inducible operons, the inducer binds to the operator
Q.3 Signaling pathways usually comprise of several intermediate steps that are arranged in the form of a cascade. What is the primary outcome of such an arrangement?
(A) Specificity of signal transduction
(B) Specificity of the cellular response
(C) Amplification of the cellular response
(D) Fine-tuning of the cellular response
Q.4 Which among the following contain(s) oxygen-rich blood in the human vascular system?
I. Right ventricle
II. Aorta
III. Pulmonary vein
(A) I only (B) I and II only
(C) I, II and III (D) II and III only
Q.5 Choose the option that lists the correct sequence of steps involved in gene therapy.
P. Injection of expression vector into patient
Q. Wild-type gene is inserted into expression vector
R. Wild-type gene is isolated and cloned
S. Wild-type gene is transcribed and translated in the patient
(A) Q, S, P, R (B) Q, P, R, S (C) R, P, Q, S (D) R, Q, P, S
Q.6 Cephalin, a biological surfactant, is
(A) choline phosphoglyceride
(B) ethanolamine phosphoglyceride
(C) glycosphingolipid
(D) sphingolipid
Q.7 The major product(s) produced by gas phase UV irradiation of 2-pentanone is (are)
(A) acetone and ethene
(B) acetic acid and propionic acid
(C) 2-pentanol
(D) cyclopentane
Q.8 If a projectile lifts off from the surface of the Earth with a speed of 11.2 km.s–1, then it can escape from the Earth’s gravitational field completely. This is called the escape velocity. If the radius of the Earth were 2 times larger and the mass 8 times larger, then the escape velocity (in km.s–1) would be
(A) 5.6 (B) 11.2 (C) 22.4 (D) 44.8
Section – B :
Q. 11 – Q. 30 carry two marks each.
Q.11 In a population growing according to the logistic growth model
(A) individuals reproduce according to their physiological capacity
(B) the per capita rate of increase approaches zero as the population nears the carrying capacity
(C) the number of births is always more than the number of deaths
(D) the birth-to-death ratio is NOT influenced by the carrying capacity
Q.12 Which part of the genomic DNA contains the sequence corresponding to the 5′ untranslated region (5′ UTR)?
(A) Exon (B) Intron
(C) Upstream of the transcription start site (D) Upstream of the promoter
Q.13 Which one of the following is NOT TRUE of RNA polymerase II?
(A) It requires a primer to initiate the transcription
(B) It makes an RNA copy of only one strand of a double-stranded DNA at any given time
(C) It does not synthesize rRNA and tRNA
(D) It catalyzes the polymerization of RNA only in the 5′?3′ direction
Q.14 Choose the option that shows the correct pairing of the cellular components with their corresponding function.
P. Dynein i. Movement of organelles
Q. Desmosome ii. Membrane vesicle
R. Endosome iii. Beating of flagella
S. Kinesin iv. Attachment of cells together
(A) P-iv, Q-i, R-ii, S-iii (B) P-iii, Q-iv, R-ii, S-i
(C) P-iii, Q-i, R-ii, S-iv (D) P-ii, Q-i, R-iv, S-iii
Q.15 An enzyme shows highest activity in the pH range 2.0 – 3.0. At pH 4.0 and pH 7.0, the enzyme exhibits 50% and 1%, respectively, of its highest activity. Which of the following states of an amino acid residue in the catalytic site is most responsible for its activity profile?
(A) A protonated Asp (B) A deprotonated Asp
(C) A deprotonated Asn (D) A protonated Asn
Q.16 The specific productivity (qp) of cellulase production by Aspergillus niger follows a linear relationship with the specific growth rate (µ) and is of the form qp = aµ + ß, where a and ß are constants. Assuming that the values of a and ß are 0.006 and 25, respectively, which type of product formation kinetics is TRUE?
(A) Growth-dependent kinetics (B) Non-growth-dependent kinetics
(C) Both growth- and non-growth-dependent kinetics (D) Inhibition kinetics
JAM 2013 Biotechnology :
Continuous culture technique at steady state (chemostat) is useful in isolating bacteria from a mixed culture. It exploits the differences in their
(A) maintenance requirements (B) speci?c growth rates
(C) rates of speci?c product formation (D) endogenous metabolism
Bio?lrn observed in the lungs of cystic ?brosis patients is composed of
(A) polysaccharides (B) polylactic acid
(C) polypeptides (D) polyethylene glycol
Match the pathogens listed in Column Iwith the diseases listed in Column H
Column I Column 11
P. Rotaviius 1. Food poisoning
Q. Leishmania 2. Diarrhea
R. Salmonella Typhimurium 3. Kala azar
S. Epstein-Barr Virus 4. Typhus fever
(A) P-z, Q-l, 11-4, 5-5
(0) P-S, Q-3, 11-4, 3-2
(B) P-Z, Q-s, R~1, so
(in) P-5, Q-i, R-3, 5-4
The time required for an E. coli to divide is less than the time required to replicate its chromosome. This is possible because
(A) of an abundance of enzymes required for replication
(B) it linearizes the chromosome and replicates from both ends
(C) only one daughter cell receives the nuclear material
(D) of multiple replication forks
A bacterial population contains a mixture of wild type and leucine auxotrophs. From this mixture, the leucine auxotrophs can be enriched by growing the mixture in minimal medium Supplemented With
(A) leucine B) penicillin (C) leucine and penicillin (D)chlorarnphenicol
Gram positive bacteria are more rigid than Gram negative bacteria because of the
(A) presence of multiple layers of peptidoglycan
(B) lack of D»amino acids in their cell wall
(C) presence of N-acetylgalactosarnine in the peptidoglycan backbone
(D) presence of lipopolysaccharide
Helicobacter pylori can survive in the highly acidic environment of human stomach because it
(A) creates an alkaline microenvironment around itself by urease action
(B) rapidly invades the stomach cells and escapes the acidic environment
(C) is capsulated and hence, is protected from acidic stress
(D) undergoes sporulation for self protection
The waxy surface of dental plaques does not allow oxygen to diffuse readily. A sample of dental plaque was inoculated into a rich medium and incubated at 37°C with vigorous shaking. However, there was no bacterial growth. The absence of growth was attributed to the following reasons
P: These bacteria are obligate anaerobes
Q: These bacteria require highly alkaline medium for growth
R: These bacteria require a very hard surface, such as that of teeth, to grow.
Which of these three reasons are likely to be correct?
(A) Only P (B) Both P and Q
(C) Both Q and R (D) Both P and R
Cellulases and hemiceliulases are in great demand nowadays for the preparation of second- generation
(A) biodiesel (B) bioplastics
(C) bioethanol (D) antibiotics