BME803C Bio-Informatics B.Tech Question Paper : wbut.ac.in

Name of the University : West Bengal University of Technology
Department : Biomedical Engineering
Degree : B.Tech
Sem : VIII
Subject Code/Name : BME-803C/Neural Network And Fuzzy Logic Control
Website : wbut.ac.in
Document Type : Previous Year Examination Question Paper

Download Model/Sample Question Paper :
2009 : https://www.pdfquestion.in/uploads/qpaper.wbut.ac.in/6680-2009BME-803C.pdf

Bio-Informatics Model Question Paper

Engineering & Management Examinations, April – 2009 :
Semester – 8 :
Time : 3 Hours
Full Marks : 70

Related : West Bengal University of Technology BME704D Neural Network & Fuzzy Logic Control B.Tech Question Paper : www.pdfquestion.in/6677.html

Model Questions

GROUP – A : ( Multiple Choice Type Questions )
1. Choose the correct alternatives for the following : 10 × 1 = 10
i) Which one is very powerful tool, as mentioned below, allowing users to formulate queries across a range of different data types via a single interface, without having to worry about underlying data structures, query languages and so on ?
a) SRS b) RFLP
c) Microsatellite d) Electrophoresis.

ii) Gene Bank is one of the principal database relevant to
a) DNA b) m-RNA
c) proteins d) c-DNA.

iii) PDB is one of the principal database concerned to
a) DNA b) RNA
c) proteins d) r-RNA.

iv) Which one of the following is the sequence similarity search tool ?
a) BLASTX b) FASTA
c) Contig d) EST.

v) ‘Dayhoff Mutation Data Matrix’ is concerned to
a) PAM matrix b) BLOSUM matrix
c) DOT Plot matrix d) Results of bacterial growth.

vi) The Needleman and Wunch algorithm is widely used for
a) local alignment b) global alignment
c) both of these d) none of these.

vii) In multiple sequence alignment, which one of the following tools is widely used ?
a) BLAST b) CLASTALW
c) EST d) SWISS-PROT.

viii) Maximum Parsimony and UPGMA methods are relevant to
a) Phylogenetic analysis b) Hierarchical analysis
c) Gene expression analysis d) Molecular data analysis.

ix) PAM and BLOSUM are involved in
a) dynamic programming b) stand alone programming
c) both of these d) none of these.

x) In FASTA format of sequence presentation, all presentable characters should bein
a) lower case b) upper case
c) binary form d) none of these.

GROUP – B : ( Short Answer Type Questions )
Answer any three of the following. 3 × 5 = 15
2. What is plasmid ? Discuss briefly the steps of the process of transcription in prokaryotes. 1 + 4
3. What is an allosteric enzyme ? Give a brief note on the process of glycolysis. 1 + 4
4. What is gene mutation ? Mention few points paying regards to repair mechanisms of DNA against mutation. 1 + 4
5. Write about the regulation of gene expression. Draw your attention to note some significance in favour of that regulatory effect. 2 + 3
6. What is Genetic Code ? Give a brief note on the process of translation in prokaryotes. 1 + 4

GROUP – C : ( Long Answer Type Questions )
Answer any three of the following. 3 8 15 = 45
7. Discuss about the main features of PAM and BLOSUM matrices along with their practical implications. 15
8. Discuss about the different methods of phylogenetic analysis. Among all of the methods which one appears as much suitable to you and why ? 12 + 3
9. Give an account on general architecture of both prokaryotic and eukaryotic genes. 15

10. Discuss briefly about A, B and Z-DNA along with their occurrence. What are positive and negative supercoilings ? 10 + 5
11. What is the linking number of DNA ? Give an account on the structure of nucleosome. 4 + 11
12. Discuss briefly on primary, secondary and tertiary structures of proteins. What is ‘domain’ in a protein structure ? 10 + 5

Biological Control System

Time Allotted : 3 Hours
Full Marks : 70
** The figures in the margin indicate full marks.
** Candidates are required to give their answers in their own words as far as practicable.

Group – A : ( Multiple Choice Type Questions )
1. Choose the correct alternatives for the following : 10 1 = 10
i) O 2 carrying capacity of haemoglobin reduces during
a) alkalosis b) acidotic coma
c) anaemia d) arythmia.

ii) Stimulation of ……………… area causes tachycardia and hypertension
a) limbic system b) hypothalamus
c) thalamus d) cerebellum.

iii) When movement of substances occurs from higher to lower concentration but with the help of carrier and without any energy expenditure the process is called
a) secondary active transport
b) endosmosis
c) facilitated diffusion
d) exosmosis.

iv) Glucagon plays an important role in the control of
a) blood pressure b) body temperature
c) blood sugar d) blood pH.

v) Hamberger phenomenon regulates
a) CO 2 transport in blood
b) O 2 transport in blood
c) nutrient transport in blood
d) excretory substance transport in blood

vi) Counter-current multiplier exchange system is mainly controlled by
a) hydrostatic pressure of glomerulus
b) medullary gradient
c) renin-angiotensin system
d) autoregulation of kidney.

vii) Influence of O 2 in reducing CO 2 carrying capacity of blood is known as
a) Bohr’s effect b) CDH effect
c) Kreb’s effect d) Donnan effect.

viii) When glucose is produced from amino acids the process is called
a) Glycogenolysis b) Glycogenesis
c) Glycolysis d) Gluconeogenesis.

ix) Glomerular filtration is favoured by
a) colloidal osmotic tension of the capillary blood
b) capillary hydrostatic pressure
c) hydrostatic pressure of Bowman’s capsule
d) all of these.

x) Design of thermoregulatory processes in human is an example of
a) closed loop system b) open loop system
c) both (a) and (b) d) none of these.

GROUP – B : ( Short Answer Type Questions )
Answer any three of the following. 3 5 = 15
2. What are the basic components of a control system ? Name the system performance characteristics which are affected by the use of feedback. 3 + 2
3. How does liver play role in the control of blood sugar ?
4. Why is H + ions secretion in DCT an important issue in regulation of acid-base balance of the body ?
5. Name the sympathetic centre of human brain that control blood pressure. How does it correct hypotension in human body ? 1 + 4
6. Explain the importance of protoporphyrin structure of haemoglobin in the regulation of O 2 uptake in blood.
7. How does kidney maintain GFR and how is renal autoregulation achieved ?