AKTU Pharmaceutical Analysis- I B.Pharm Old Question Paper : Dr. A.P.J. Abdul Kalam Technical University

University : Dr. A.P.J. Abdul Kalam Technical University, Uttar Pradesh
Degree : B.Pharm
Semester : I
Subject : Pharmaceutical Analysis- I
Document Type : Old Question Paper/Question Bank
Website : https://aktu.ac.in/

Download Model/ Sample Question Papers : https://www.pdfquestion.in/uploads/6176-analysis.pdf

AKTU Pharmaceutical Analysis- I Old Question Paper

B. Pharm. First Semester Examination (2008-09)
Paper Code : PHAR- 112 ID: 5093
M.M-80 marks
Time : 3 hrs.

Related / Similar Question Paper :
UPTU B.Pharm Pathophysiology Question Paper

Section A

(1×16=16)
Q1. Henderson- Hasselbach equation for acidic buffer is ___________. (1)
Q2. Equation for solubility product of AgCl is ___________. (1)
Q3. Fluorescein indicator is used in _____________ titrations. (1)

Q4. Precipitation occurs when ionic product __________ solubility product. (1)
Q5. When observations are taken on the same day, then precision is known as_____. (1)
Q6. In acidic solution, equivalent weight of KMnO4 is _________. (1)

Q7. The pH of aqueous solution of NaCl is________. (1)
Q8. AlCl3 is a lewis _______. (1)
Q9. No. of moles of solute per __ g of the solvent is known as molality of the solution. (1)
Q10. Iodine is readily soluble in aqueous solution containing________. (1)

Q11. ___________ is used as washing solution in the gravimetric analysis of Aluminium. (1)
Q12. All the water of crystallization of CuSO4.5H2O is lost at _______ 0C. (1)

Q13.Match the following (4 x 1)
a. Ferric ammonium sulphate (i) NaCl Vs AgNO3
b. Potassium chromate (ii) HCl Vs NH4OH
c. Phenolphthalein (iii) NH4SCN Vs AgNO3
d. Methyl orange (iv) NaOH Vs CH3COOH

Section B

Note : Attempt any 6 questions. (6×4=24)
Q1. What are methods to reduce systematic errors in Pharmaceutical Analysis?
Q2. Define “Law of Mass Action”?
Q3. Explain titration of string acid with alkalies by using titration curves?

Q4. What is Colloid? Explain the difference between lyophobic and lyophilic colloids?
Q5. Explain gravimetric determination of BaSO4?
Q6. Explain Fajan’s method in detail?

Q7. Write about Oxidation – Reduction titration curve?
Q8. Calculate the ionic strength of these solutions
(a) 0.16M NaClO4
(b) 0.20M CuSO4

Section C

Note : Attempt any 4 questions. (4×10=40)
Q1. 25.0ml of 0.1M HCl is titrated with 0.10M NaOH. Calculate the pH at the
(a) Stand of titration
(b) After addition of 5.0ml titrant
(c) After addition of 25.0ml titrant
(d) After addition of 30.0ml of titrant

Q2. Explain the following with suitable examples
(a) Different type of co-precipitation
(b) Digestion
(c) Filteration methods
(d) Washing of precipitate

Q3. (a) Explain common ion effect and ionic product of water? (6)
(b) Write a note on choice of indicator? (4)
Q4. (a) Write theory of Redox titration? (5+5)
(b) What are the advantages of Cerric Ammonium Sulphate Ores Iodine?

Q5. Write notes on (any four)
(a) Thermogravimetric Curves
(b) Buffer Soluiton
(c) Mixed Indicators
(d) Henderson – Hasselbach equation.

Syllabus

Unit I : 10 Hours
(a) Pharmaceutical analysis- Definition and scope
i) Different techniques of analysis
ii) Methods of expressing concentration
iii) Primary and secondary standards.

iv) Preparation and standardization of various molar and normal solutions- Oxalic acid, sodium hydroxide, hydrochloric acid, sodium thiosulphate, sulphuric acid, potassium permanganate and ceric ammonium sulphate

(b) Errors : Sources of errors, types of errors, methods of minimizing errors, accuracy, precision and significant figures
(c) Pharmacopoeia, Sources of impurities in medicinal agents, limit tests.

Unit II : 10 Hours
Acid base titration : Theories of acid base indicators, classification of acid base titrations and theory involved in titrations of strong, weak, and veryweak acids and bases, neutralization curves

Non aqueous titration : Solvents, acidimetry and alkalimetry titration and estimation of Sodium benzoate and Ephedrine HCl

Unit III : 10 Hours
Precipitation titrations : Mohr’s method, Volhard’s, Modified Volhard’s, Fajans method, estimation of sodium chloride.

Complexometric titration : Classification, metal ion indicators, masking and demasking reagents, estimation of Magnesium sulphate, and calcium gluconate.

Gravimetry : Principle and steps involved in gravimetric analysis. Purity of the precipitate: co-precipitation and post precipitation, Estimation of barium sulphate.
** Basic Principles, methods and application of diazotization titration.

Unit IV : 08 Hours
Redox titrations
(a) Concepts of oxidation and reduction
(b) Types of redox titrations (Principles and applications) Cerimetry, Iodimetry, Iodometry, Bromatometry, Dichrometry, Titration with potassium iodate.