Neuro Basic Sciences M.Ch Question Bank : web.tnmgrmu.ac.in
Name of the University : The Tamilnadu Dr. M.G.R. Medical University
Degree : MASTER OF CHIRURGIAE (M.Ch.)
Branch : BRANCH II – NEURO SURGERY
Subject Code/Name : 1563/NEURO BASIC SCIENCES
Paper : I
Document Type : Question Bank
Website : web.tnmgrmu.ac.in
Download Model/Sample Question Paper :
(3 Years Course) PART-I :
1997-2000 : https://www.pdfquestion.in/uploads/web.tnmgrmu.ac.in/4541-1-171581KC.pdf
2001-2010 : https://www.pdfquestion.in/uploads/web.tnmgrmu.ac.in/4541-2-171581KU.pdf
Candidates admitted upto 2005-06 to 2007-08 :
(6 Years Course) PART-II :
2009-2013 : https://www.pdfquestion.in/uploads/web.tnmgrmu.ac.in/4541-3-181581KU.pdf
Neuro Basic Science :
FEBRUARY – 2009 :
[KU 036] Sub. Code: 1581
M.CH DEGREE EXAMINATIONS
Related : TNMGRMU Neurochemistry & Neuropathology M.Ch Question Bank : www.pdfquestion.in/4534.html
(Higher Specialities)
(Revised Regulations for 3 years course)
Branch II – Neuro Surgery
Paper I : NEURO BASIC SCIENCES
Q.P. Code: 171581
Time: Three hours
Maximum: 100 Marks
ANSWER ALL QUESTIONS :
Draw suitable diagrams wherever necessary. :
I. Essays: 2 x 20 = 40 Marks
1. Describe the Neuroanatomy of cerebral cisterns and surgical importance of sylvan fissure.
2. Classification of Astrocytoma – Discuss.
II. Write short notes on: 10 X 6 = 60 Marks
1. Neuro transmitters.
2. Terratogenicity of antiepileptics.
3. Cortical Blindness.
4. Dorsal root entry zone and its importance.
5. Afferent and efferent connections of cerebellum.
6. Secretion of CSF.
7. Embryology of vertebral body.
8. Calcium antagonists in vasospasm.
9. Anatomical landmarks of skull and their use in Neurosurgery.
10. Central pontine and extra pontine myeliuosis.
August 2009 :
I. Essays: 2 x 20 = 40 Marks
1. Discuss the pathophysiology of diffuse axonal injury.
2. Discuss the pharmacological management of cerebral edema.
II. Write short notes on: 10 X 6 = 60 Marks
1. Neuron specific enolase.
2. Amitriptyline.
3. H-reflex.
4. Polymerase chain reaction.
5. Sodium channels.
6. Neural transplantation.
7. Immunohistochemistry.
8. Brain biopsy.
9. Radio-surgery.
10. Mini mental status examination.
February 2010 :
I. Essays: 2 x 20 = 40 Marks
1. Classification of pituitary adenomas and their therapeutic implication.
2. Microsurgical anatomy of CP angle with emphasis on landmarks for facial nerve identification.
II. Write short notes on: 10 X 6 = 60 Marks
1. Pain pathways.
2. Sodium channels.
3. Radiation injury to CNS.
4. Embryology of vertebral body.
5. WHO grading of meningioma.
6. Immunotherapy for gliomas.
7. Cortical malformations.
8. Pathophysiology of lumbar disc.
9. Phenytoin.
10. Fungal granulomas.
August 2011 :
I. Elaborate on :
1. Discuss the development of neural tube and the embryological basis for Neural Tube defects.
2. Enumerate the various Neurotransmitters, their distribution and functions.
II. Write notes on :
1. Immuno histo chemitry.
2. Blood supply of internal capsule.
3. Pathophysiology of cerebral vaso spasm.
4. Grading system for Gliomas.
5. Autoregulation of cerebral blood flow.
6. Tumour markers in the diagnosis of pineal tumours.
7. Cross-section of medulla at the level of olive.
8. Classification of nerve fibres.
9. Subarachnoid cisterns in the posterior cranial fossa.
10. Capases and Calpains.
AUGUST 2012 :
I. Elaborate on :
1. Gross and microscopic anatomy of the pituitary gland with its relevance to classification of pituitary adenomas.
2. Deep venous drainage system of the brain.
II. Write notes on:
1. Anatomical relationships of the Foramen of Monro and its relevance to surgery.
2. Microsurgical anatomy of cerebellopontine angle cistern.
3. Factors determining cerebral blood flow.
4. Normal electroencephalogram.
5. Dopamine.
6. Intracranial pressure wave.
7. Blood supply of the spinal cord.
8. Role of tumour markers in diagnosis of posterior third ventricular tumours.
9. Brain stem auditory evoked potential.
10. Phenytoin.
AUGUST 2013 :
I. Elaborate on : (2X15=30)
1. What are the bony and ligamentous anatomical relationships of the atlanto axial joint? Mention their relevance to maintaining atlanto axial stability.
2. Describe the anatomy of the cavernous sinus and add a note on its relevance to the surgical approaches to lesions within the cavernous sinus.
II. Write notes on : (10X7=70)
1. Mannitol.
2. Microscopic pathology of astrocytomas and their WHO classification.
3. Recesses of the third ventricle.
4. Acetazolamide.
5. Blood brain barrier.
6. Foramen magnum.
7. Pathway for conduction of pain sensation.
8. Motor evoked potential.
9. Innervation of urinary bladder.
10. Acetyl choline.
Theory Syllabus :
PART II (6 years course) :
Neuroanatomy :
** Embryology of the nervous system
** Descriptive gross and microscopic anatomy
** Cross sectional anatomy relevant to interpretation of CT/MRI
** Microsurgical anatomy in relation to various operative approaches
Neurophysiology :
** Physiology of intracranial pressure
** Physiology of motor, sensory systems and understanding the basis for clinical signs/symptoms in pathological states
** Physiology of autonomic nervous system
** Physiological basis for EEG, Evoked potentials and nerve conduction/Electromyography studies
** Interpretation of EEG/ Evoked potential studies
Neurochemistry :
** General principles of Neurochemistry
** Neurotransmitters – Their distribution, synthesis and functions
** Neuroreceptors and their actions
** Biochemical changes in trauma and ischemia
Neuropathology :
** Pathological changes in congenital, traumatic, inflammatory, infectious and neoplastic illnesses of the central and peripheral nervous system
** Latest WHO classification of brain tumours and their clinical relevance
** Basic molecular classification of brain tumours and their clinical relevance
** Basic knowledge of principles of immunohistochemistry and its role in classification of brain neoplasms
** Bacteriology, Virology and Parasitology with reference to common neurological infections