Recent Advances in Medical Oncology DM Question Bank : web.tnmgrmu.ac.in

Name of the University : The Tamilnadu Dr. M.G.R. Medical University
Degree : D.M
Branch : Branch VII – Medical Oncology
Subject Name : 1304/RECENT ADVANCES IN MEDICAL ONCOLOGY
Paper : IV
Document Type : Question Bank
Website : web.tnmgrmu.ac.in

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TN MGRMU Medical Oncology Question Paper

August 2008 :
Sub. Code: 1304
D.M. DEGREE EXAMINATION

Related : TNMGRMU Surgical Anatomy & Applied Anatomy & Recent Advances MD Question Bank : www.pdfquestion.in/4359.html

(Higher Specialities)
(Revised Regulations)
Branch VII – Medical Oncology
Paper IV : RECENT ADVANCES IN MEDICAL ONCOLOGY
Q.P. Code: 161304
Time: Three hours
Maximum: 100 Marks
Answer ALL questions :
Draw suitable diagrams wherever necessary. :
I. Essays: 2 x 20 = 40
1. Discuss the pathophysiology of hemopoesis and the current status of colony stinmulating factor in the management of infectious complications in subjects with febrile neutropenia following myelosuppressive chemotherapy.
2. Elaborate the role of molecular targetted therapy in the treatment of squamous cell cancer of the head and neck.
II. Write short notes on: 10 x 6 = 60
1. Directed donation.
2. Ostroarticular allograft.
3. Thrombopoietin.
4. Mammalien target of rapamycin inhibitors (MTOR).
5. Graft versus myeloma effect.
6. Proteosome Inhibitor.
7. Thallium – 201 (Imaging).
8. Terminally ill Children – issue of support.
9. Neurocognitive sequeale of children treated with radiation.
10. Central venous catheter infection.

February 2009

I. Essays: 2 x 20 = 40
1. Write short assay on Epigenetics.
2. ‘Cancer is a multistep process’ Explain this with example of colon cancer. What could be possible interventions at each step?
II. Write short notes on: 10 x 6 = 60
1. Bortezomib.
2. Treatment of CNS leukemia.
3. T cell non Hodgkin’s Lymphoma.
4. Allogeneic stem cell transplantation for immunodeficiency diseases.
5. Role of immunohistochemistry in the diagnosis of unknown primary.
6. Management of Invasive aspergillosis.
7. Treatment of superior venal cava obstruction.
8. Differential diagnosis of ovarian mass in a 15 year old girl.
9. Communication skills in oncology care.
10. Merits and demerits of treatment in asymptomatic early stage prostate cancer.

August 2009

I. Essays: 2 x 20 = 40
1. Discuss briefly on the recent development in pathology, molecular biology and management of glioblastoma multiforme.
2. Management of imitanib resistant chronic myeloid leukemia.
II. Write short notes on: 10 x 6 = 60
1. K RAS.
2. RECIST PD – 20.
3. Lepatinib.
4. IGRT (image guided Radiotherapy).
5. Multikinase inhibitors.
6. Chemoport.
7. GVHD.
8. Molecular targeted therapy in renal cell carcinoma.
9. Chemoprevention.
10. Management of mesothelioma.

August 2011

Answer ALL questions in the same order. :
I. Elaborate on :
1. Discuss in detail Adoptive cell therapy in treatment of Cancer.
2. Discuss the current status of individualized treatment for Cancer (Tailored Therapy) in Medical Oncology.
II. Write notes on :
1. Electronic Medical Records.
2. Robotic Surgery in Oncology.
3. Bendamustine.
4. Radiation induced Cardiotoxicity.
5. Olaparib.
6. Image Guided Radiaotherapy (IGRT).
7. Genitourinary Rhabdomyosarcoma.
8. Carcinosarcoma of uterus.
9. Thaliomide.
10. Myelofibrosis.

August 2012

I. Elaborate on : Pages Time Marks
1. Discuss in detail the role Targeted therapy and recent advances in the SystemicManagement of Colorectal Cancers.
2. Critically analyse the role and issues regarding Intraperiotoneal Chemotherapy in Epithelial Ovarian Cancer.

II. Write notes on :
1. Indications and contraindications of Total Parenteral Nutrition in Cancer Patients.
2. Algorithm for Cancer Pain Management.
3. Utility of Erlotinib in Solid Tumour Oncology.
4. Definition and Indications of Haploidentical Stem cell Transplantation.
5. Recent advances in Systemic therapy in Non Small Cell Lung Cancer.
6. Accelerated Approval of Cancer Drugs.
7. Definition and issues involved in Euthanasia and Physician Assisted Suicide.
8. Clinical Indications and Toxicity of Trastuzumab.
9. Recent Advances in the management of Hormone Refractory Prostate Cancer.
10. Current role of PET Scan in patients with Lymphomas.

August 2013

I. Elaborate on :
1. Discuss in detail the role of Targeted therapy in Oncology.
2. Indications, contraindications, methodology and side effects of Allogenic bone marrow transplant .

II. Write notes on :
1. Nanotechnology in oncology.
2. Active specific immunotherapy for cancer.
3. 3rd generation Pgp (P-glycoprotein) inhibitors.
4. Differentiating agents in the treatment of cancer.
5. HNPCC prevention.
6. Sorafenib.
7. Radiofrequency ablation.
8. Vandetanib.
9. Metronomic chemotherapy.
10. Predictive molecular tests in cancer management.

August 2014

I. Elaborate on :
1. Recent advances in treatment of HER 2 Positive Breast cancer.
2. Discuss in detail about cytogenetics, molecular abnormalities, prognostic factors and newer therapies in Acute Myeloid Leukemia.

II. Write notes on :
1. Eribulin.
2. Targeted therapy in Hodgkin’s Lymphoma.
3. Ramucirumab in colorectal cancer.
4. Nutritional assessment and intervention in cancer patients.
5. Role of Androgen receptor in breast cancer management.
6. Immunotherapy in malignant melanoma.
7. Comment on Surgery vs Observation following Neo adjuvant chemo radiation in locally advanced rectal cancer.
8. Describe charged particle beams in radiation and mention the advantages and disadvantages of Proton and Carbon beam therapy.
9. Granulosa cell tumours of the ovary.
10. How do you assess cost-effectiveness and use it in decision making?