Molecular Biology, Clinical Biochemistry, Function Tests, Endocrinilogy, Immunology, Recent Advances in Biochemistry M.Sc Non Medical Question Bank : web.tnmgrmu.ac.in
Name of the University : The Tamilnadu Dr. M.G.R. Medical University
Degree : M.Sc Non Medical Degree Examination
Subject Code/Name : 1203/Molecular Biology, Clinical Biochemistry, Function Tests, Endocrinilogy, Immunology, Recent Advances Ii Biochemistry
Year : FINAL YEAR
Paper : III
Document Type : Question Bank
Website : web.tnmgrmu.ac.in
Download Model/Sample Question Paper :
2012-2013 : https://www.pdfquestion.in/uploads/web.tnmgrmu.ac.in/4065-281203LA.pdf
Sub. Code: 1203
M.Sc BIOCHEMISTRY DEGREE EXAMINATION
Candidates admitted from 2008-2009 batch
PAPER III – MOLECULAR BIOLOGY, CLINICAL BIOCHEMISTRY, FUNCTION TESTS, ENDOCRINILOGY, IMMUNOLOGY, RECENT ADVANCES IN BIOCHEMISTRY
Q.P. Code : 281203
Time : Three hours
Maximum :100marks
Answer All questions. :
I. Elaborate on :
1. What is Blot transfer technique? Briefly explain the various types of blot transfer techniques and their applications.
2. What is a buffer? Explain how the various buffers help to maintain acid base status.
II. Write notes on :
1. What is genetic code? What are the features of the genetic code?
2. What are Proto-oncogenes? Explain the normal mechanism of action of proto-oncogenes and how they are activated to oncogenes.
3. Anion gap.
4. Monoclonal antibodies and their clinical significance.
5. Explain mechanism of hormone action through cytosolic or nuclear receptors.
6. Transport of iron in plasma and its storage.
7. What are the biochemical investigations to assess the tabular function of kidneys?
8. Alkaline phosphatase and its clinical importance.
9. Enumerate and describe briefly the pre-analytical errors in clinical laboratory
10. Laboratory Information System.
OCTOBER 2012 :
(180 Min)
Answer ALL questions in the same order. :
I. Elaborate on :
1. Describe in detail Recombinant DNA technology and its application in medicine. Add a note on molecular scissors.
2. How is acid- base balance regulated in the body?
II. Write Notes on :
1. Investigations to be performed in a case of Nephrotic syndrome.
2. Estimation of blood glucose with a note on sample required, interferences and reference range.
3. Describe the various post-transcriptional modifications.
4. Mention the normal levels of serum electrolytes. Detail about the sodium homeostasis in our body.
5. Evaluation of thyroid function in a case of goiter.
6. Hyperuricemia.
7. Describe in detail western blotting technique and its applications.
8. Describe about mitochondrial DNA.
9. Describe the various tumour markers and their applications.
10. Estimation of amylase in the laboratory with a note on sample required and its clinical applications.
APRIL 2013 :
I. Elaborate on: (2×20=40)
1. How is uric acid produced in the body? Add a note on disorders associated with it.
2. Describe in detail protein synthesis and the various post-translational modifications of proteins.
II. Write notes on : (10X6=60)
1. Describe the various stages of cell cycle with a note on its regulation.
2. Define mutation. Classify & describe the various types with examples.
3. Describe the types of DNA damage & repair mechanism.
4. Describe the mechanism of action of Type I hormones.
5. What are the various diagnostic & prognostic tests to be performed in a diabetic patient.
6. How is calcium homeostasis maintained in our body?
7. Describe in detail the structure , types and functions of Immunoglobulins.
8. CSF analysis and its application.
9. Estimation of Gamma Glutamyl Transferase(GGT).
10. Prenatal diagnosis of inborn errors of metabolism.