General Principles of Radio Therapy including Biology & Oncology PG DMRT Question Bank : web.tnmgrmu.ac.in

Name of the University : The Tamilnadu Dr. M.G.R. Medical University
Degree : PG Diploma in Medical Radio Therapy (DMRT)
Subject Code/Name : 3026 General Principles of Radio Therapy including Radio-Biology & Oncology
Paper : II
Document Type : Question Bank
Website : web.tnmgrmu.ac.in

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General Principles of Radio Therapy including Radio-Biology & Oncology :
September 2008 :
I. Essay questions : (2 X 20 = 40)
1. What is meant by OLIGODENDROGLIOMA and the approach to management – Discuss.
2. Describe RETINOBLASTOMA and its management.

II. Write short notes on : (10 X 6 = 60)
1. Boost field.
2. DNA (Deoxy Ribonucleic Acid).
3. P 53 Gene.
4. HDR Brachy.
5. Mould therapy.
6. Basal cell carcinoma – skin.
7. Her 2 neu.
8. Human papiloma virus.
9. Hemibody Radiotherapy.
10. Hypoxic sensitizers.

March 2009 :
I. Essay questions : (2 X 20 = 40)
1. Discuss radiation response modulators with suitable examples and diagrams under the following heading :
a) Chemical radio sensitizers and protectors.
b) Biologic response modifiers.
2. List some of the clinical situations where radiochemotherapy has been more advantageous. Discuss the rationale and various techniques that can be followed in radiochemotherapy.

II. Write short notes on : (10 X 6 = 60)
1. Tumour volumes as per ICRU Report No.50.
2. Cellcycle specific chemotherapeutic drugs.
3. Discuss field matching with suitable examples.
4. Radio biologic rationale of Brachytherapy.
5. Intraoperative radiation therapy.
6. Drug resistance and the genetics involved in it.
7. Explain with graphs a) Radio sensitivity b) Radio curability
c) Radio resistant. d) Therapeutic ratio.
8. Which all cranial nerves get involved in a nasopharyngeal cancer. Discuss with diagrams.
9. Photodynamic therapy.
10. Hyperthermia.

September 2009 :
I. Essay questions : (2 X 20 = 40)
1. Discuss about the areas of multi pronged approach in oncology and its value.
2. Carcinoma cervix and radiotherapy – Discuss.

II. Write short notes on : (10 X 6 = 60)
1. Oxygen enhancement ratio.
2. Pain syndromes and therapy.
3. Acute radiation syndromes – (whole body radiation – humans).
4. Organs TD 5/5 tissue doses and morbidity.
5. Mycosis fungoides.
6. Plasma cell tumor.
7. Beta HCG.
8. Granulocyte colony stimulating factor.
9. Cell cycle and irradiation.
10. Iodine 131.

September 2010 :
I. Essay questions : (2 X 20 = 40)
1. Discuss the biologic effects of radiation.
2. Discuss electron therapy.

II. Write short notes on : (10 X 6 = 60)
1. Radiation cataract.
2. Hypoxic cell sensitizers.
3. Linear energy transfer.
4. Rectal morbidity.
5. Radio sensitizers.
6. Hemibody Radiotherapy.
7. Benign lesions and radiotherapy.
8. Cell cycle and irradiation.
9. Bloom Richardson grading in breast cancer.
10.Oncogenes and tumour suppressor genes.