Name of the University : Savitribai Phule Pune University
Department : Biotechnology
Degree : B.E
Subject Code/Name : Bioprocess Equipment Design
Sem : I
Website : unipune.ac.in
Document Type : Question Paper
Download Model/Sample Question Paper : https://www.pdfquestion.in/uploads/unipune.ac.in/6996-be_oct2011.pdf
Bioprocess Equipment Design Paper :
B.E. (Biotechnology) (2008 Course) (415465) (Sem. – I)
Time : 3 Hours
Max Marks : 100
Related : Savitribai Phule Pune University Natural Gas Technology B.E Question Paper : www.pdfquestion.in/6995.html
Instructions to candidates :
1) Answer three questions from Section I and three questions from Section II.
2) Answer to the two sections should be written in separate answer boooks.
3) Draw neat diagrams whenever necessary.
4) Figures to the right indicate full marks.
5) Make necessary assumptions wherever required.
SECTION-I :
Q1) a) Explain codes and standards used in design. [6]
b) Explain the generalized design process in detail. [6]
c) Draw and explain stress-strain curve for: [6]
i) Ductile material
ii) Brittle material
OR
Q2) a) Define following mechanical properties of materials: [6]
i) Creep ii) Toughness
iii) Elasticity iv) Resilience
v) Malleability vi) Plasticity
b) Explain following theories of failure under static load: [12]
i) Maximun normal stress theory.
ii) Maximum shear stress theory.
iii) Maximum distortion energy.
Q3) a) Describe the design of plain head, shallow dished head, and hemispherical head with neat sketch. [8]
b) Discuss the material used for the construction of high pressure vessel. [4]
c) A hydraulic pipe 7.5 cm internal diameter is to be operated at an internal pressure of 50kg/cm2. Calculate the thickness of pipe if the stress must not exceed 240 kg/cm2. [4]
OR
Q4) a) A vessel is to be designed to withstand an internal pressure of 150 MN/m2. An Internal diameter of 30 cm is specified, and steel having yield point of 450 MN/ m2 has been selected. Calculate the wall thickness required by the various theories with a factor of safety 1.5 and µ = 0.3. [12]
b) Why it is necessary to consider the corrosion allowances while specifying the final thickness of the vessel? [4]
Q5) a) Calculate the diameter of a shaft used in agitation system. Torque acting over the Shaft is 115000 kg-cm, While bending moment acting over the shaft is equal to 34600 kg-cm2. Ultimate tensile strength of shaft material is equal to 6900 kg/cm2. Ultimate shear stress is 75% of ultimate tensile stress. Factor safety used is 6.0. [8]
b) Explain various types of jackets with neat sketches. [8]
OR
Q6) a) Comment on heat transfer in agitated vessel. [8]
b) What are the types of agitators? Explain each with a neat sketch. [8]
SECTION-II :
Q7) a) Explain the operation, application and steps for the design of shell and tube heat exchanger. [8]
b) What is the function of baffles in a heat exchanger? Explain their classifications. [4]
c) Explain the classification and selection criteria of an evaporator system. [6]
OR
Q8) Design an exchanger to sub-cool condensate from a methanol condenser from 95oC to 40oC. Flow rate of methanol is 1,00,000 kg/hr. Brackish water (sea water) will be used as a coolant, with a temperature rise from 25oC to 40oC of an exchanger having 20mm O.D and 16mm I. D. steel tubes of 4.83m length. At a first estimate take an overall heat transfer resistance coefficient as 600 W/m2oC and validate your design.
Q9) a) Explain the optimum sieve plate performance diagram. [6]
b) A sieve plate distillation column is used for certain operation. Calculate the plate efficiency using Van Winkle’s correlation.
Given data:
Density of liquid = 925 kg/m3, Density of vapour = 1.35 kg/m3
Viscosity of liquid = 0.34 × 10-3Ns/m2, Viscosity of vapour = 10 × 10-6 Ns/m2,
Liquid diffusivity (light key components) = 4.64 × 10-9 m2/s
Height of weir = 50mm, hole area = 0.038m2,
Total column cross sectional area = 0.5m2, superficial vapour velocity = 1.62 m/s, liquid surface tension = 60 × 10-3 N/m. [10]
OR
Q10) a) Define following types of plate efficiency: [9]
i) Murphree plate
ii) Murphree point
iii) Overall plate (column)
b) Explain AIChE method for calculation of plate efficiency. [7]
Q11) a) Describe downstream processing operations used in fermentation processes. [10]
b) What are the types of cartridge filtration? Write down its applications in fermentation and cell culture. [6]
OR
Q12) a) Write short notes on: [8]
i) TFF system
ii) Validation of filter
b) Explain steam sterilization procedure in detail. [8]