Name of the University : The Tamilnadu Dr. M.G.R. Medical University
Degree : MASTER OF CHIRURGIAE (M.Ch.)
Branch : BRANCH IX – ENDOCRINE SURGERY
Subject Code/Name : 1904/RECENT ADVANCES IN ENDOCRINE SURGERY AND INVESTIGATIONS FOR ENDOCRINE DISEASES
Paper : II
Document Type : Question Bank
Website : web.tnmgrmu.ac.in
Download Model/Sample Question Paper :
2012-2014 : https://www.pdfquestion.in/uploads/web.tnmgrmu.ac.in/4605-181904KU.pdf
Recent Advances In Endocrine Surgery :
AUGUST 2012 :
Sub. Code: 1904
M.Ch – ENDOCRINE SURGERY
Paper – IV : RECENT ADVANCES IN ENDOCRINE SURGERY AND INVESTIGATIONS FOR ENDOCRINE DISEASES
Related : The Tamilnadu Dr. M.G.R. Medical University Endocrine Surgery-General M.Ch Question Bank : www.pdfquestion.in/4603.html
Q.P. Code: 181904
Time : 3 hours
Maximum : 100 marks
(180 Min)
Answer ALL questions in the same order. :
I. Elaborate on :
1. Management of Regional Lymph Nodes in Papillary and Medullary Thyroid Cancer.
2. Open Right Anterior Adrenalectomy and Right Anterior Laparoscopic Adrenalectomy. Mention the advantages and disadvantages in each procedure.
II. Write notes on :
1. Sodium – iodide symporter (NIS) gene therapy for undifferentiated thyroid carcinoma.
2. Role of Touch Imprint Cytology in the management of a thyroid nodule.
3. CT scan and NP-59 iodocholesterol scan in the diagnosis Adrenal cortical Tumors.
4. Pentavalent DMSA scan in the management of medullary carcinoma of thyroid.
5. Management of lymphoma of thyroid.
6. I131 MIBG in the management of recurrent pheochromocytoma.
7. Recurrent Laryngeal Nerve suturing during thyroid surgery.
8. Nuclear scintigraphy in the diagnosis of parathyroid adenoma.
9. Types of thyroplasty in the management of Recurrent Laryngeal Nerve injury.
10. Quick PTH assay.
AUGUST 2013 :
I. Elaborate on: (2X15=30)
1. Laparoscopic surgery for adrenal and pancreatic tumours.
2. Role of genetic analysis in management of endocrine tumours.
II. Write notes on: (10X7=70)
1. Isotope scan techniques for parathyroid localization.
2. Role of percutaneous injection techniques in management of thyroid tumours.
3. Bethesda system of thyroid cytology classification.
4. Intra-operative ultrasound in endocrine surgery.
5. Thyroid Receptor Antibody testing.
6. Redifferentiation therapy for thyroid tumours.
7. Role of surgery in metastatic thyroid cancer.
8. Touch imprint cytology.
9. Intraoperative anaesthetic management of pheochromocytoma.
10. Tracheal and esophageal involvement by thyroid cancer – management.
AUGUST 2014 :
I. Elaborate on: (2 x 15 = 30)
1. Detail the various investigations for the diagnosis of neuroendocrine tumour of gut. Discuss its management and explain molecular targeted therapy.
2. Molecular mechanism, diagnosis and management of primary Hyperaldosteronism
II. Write notes on: (10 x 7 = 70)
1. Clinical application of corticotrophin releasing hormone stimulation test
2. Management of persistent hyperparathyroidism after Renal transplantation
3. Parathyroid carcinoma and parafibromin
4. Advanced MRI technique in diagnosing pituitary tumours
5. Sclerostin
6. 18F- Fluorodeoxyglucose PET scan in the treatment of Adrenocortical carcinoma
7. Calcimimetics and calcilytic drugs in the management of bone and mineral disorder
8. Liquid Chromatography Tandem mass Spectrometry in Endocrine practice
9. Dehydroepiandrosterone replacement therapy-indications and clinical use
10. Temozolomide – clinical use.
Theory Syllabus :
(I).Pituitary
1. Hypothalamus and pituitary anatomy and its relation to adjacent structure
2. Pituitary embryogenesis
3. Physiology and secretion of various hormones like
** Growth hormone
** TSH
** ACTH
** Prolactin
** LH
** FSH
** Melanocyte Stimulating Hormone
4. Physiology and secretion of insulin like growthfactor.
5.Pathology of various pituitary adenomas and prognostic clinical, pathological classification of pituitary endocrine tumour.
6. Diagnosis of various pituitary diseases like
** Acromegaly
** Prolactinomas
** Cushings disease
** TSH producing adenoma
7. Pituitary tumour management in pregnancy
8. Pituitary apoplexy
(II).Thyroid :
1. Demonstrate normal thyroid anatomy in a cadaver or in the operating room, including the thyroid gland, its vascular supply and venous drainage, the parathyroid glands, recurrent laryngeal nerves, strap muscles, and platysma.
2. Normal variants in recurrent laryngeal nerve anatomy including frequency
3. Normal thyroid embryogenesis and descent.
4. Normal thyroid hormone synthetic pathway including iodine metabolism and feedback mechanisms.
5. Impact of specific medications on the thyroid hormone synthetic pathway and thyroid function.
6. Impact of aging and various diseases ofthe thyroid hormone synthetic pathway and thyroid function.
7. Appropriate thyroid function testing for the following clinical scenarios, including interpretation of predicted test results :
** Thyroid nodule
** Goiter
** Hyperthyroidism
** Hypothyroidism
** An algorithm development that includes pertinent history, examination findings, and diagnostic evaluation of
** A palpable thyroid nodule
** A nodule discovered on ultrasound performed for thyroid pathology
8. Recognition, evaluation, and management of the following early postoperative complications :
** Hematoma
** Hypocalcaemia
9. Outpatient management of the following postoperative conditions
** Thyroid hormone replacement, postoperative
** Postoperative hypocalcaemia
** Postoperative voice changes
10. Algorithms for the evaluation and treatment of :
** Well-differentiated thyroid cancer
** Medullary thyroid cancer
** Thyroid lymphoma
** Anaplastic thyroid cancer
11. Risk factors for well-differentiated thyroid cancer, medullary thyroid cancer, and anaplastic thyroid cancer.
12. Algorithms for the evaluation and treatment of hyperthyroidism due to Graves’ disease, toxic nodule, medications, pregnancy.
13. Clinical presentation of thyroid storm and outline the treatment of thyroid storm.
14. Algorithm development for the evaluation and management of nontoxic multinodular goiter, including substernal goiter with and without airway involvement.
15. Pathophysiology of :
** Multinodular goiter
** Grave’s disease
** Thyroid cancer
16. Operative approaches to thyroid pathology
17. Staging and prognosis in thyroid cancer
18. Recognition and treatment of common postoperative complications
** Hematoma
** Hypocalcemia
** Thyroid storm
** Voice changes