Name of the University : The Tamilnadu Dr. M.G.R. Medical University
Degree : D.M
Branch : Branch VII – Medical Oncology
Subject Name : 1302/General Oncology, Tumour Pathology, Radiology & Nuclear Medicine
Paper : I
Document Type : Question Bank
Website : web.tnmgrmu.ac.in
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General Oncology :
August 2008 :
Sub. Code: 1302
D.M. DEGREE EXAMINATION
Related : TNMGRMU Medical Oncology Including Therapy, Epidemiology & Rehabilitation DM Question Bank : www.pdfquestion.in/4425.html
(Higher Specialities)
(Revised Regulations)
(Common to All Regulations)
Branch VII – Medical Oncology
Paper II– GENERAL ONCOLOGY, TUMOUR PATHOLOGY, RADIOLOGY AND NUCLEAR MEDICINE
Q.P. Code: 161302
Time: Three hours
Maximum: 100 Marks
Answer ALL questions :
Draw suitable diagrams wherever necessary. :
I. Essays: 2 x 20 = 40
1. Attenpt a histological classification of germ cell tumours of the testes and discuss the treatment options for an young unmarried adult with a testicular tumour and secondary metastasis in the lung.
2. Discuss the diagnosis, management and follow up of patients with acute promyclocytic leukemia and comment on the salvage options of relapsed disease.
II. Write short notes on: 10 x 6 = 60
1. Merkel cell tumour.
2. Pontine glioma.
3. Selective Hepatic arfery embolisation.
4. Total androgen blockade.
5. Neoplastic pemphigus.
6. Mantle zone lymphoma.
7. Psendomyxoma peritonii.
8. Nilotinib.
9. Carcinoid syndrome.
10. Ritchers syndrome.
February 2009 :
I. Essays: 2 x 20 = 40
1. A 9 year old child has been diagnosed to have bilateral proptosis. Fine needle aspiration biopsy is suggestive of round cell tumour. How will you approach to diagnosis. Give rationale for each investigation.
2. Discuss briefly tumour heterogeneity.
II. Write short notes on: 10 x 6 = 60
1. Pathology of endometrial cancer.
2. Stomach Cancer: Investigations and their interpretation.
3. Multiple Myeloma: Response Criteria.
4. Beta 2 microglobulin.
5. Opioid for advanced cancer.
6. Radiolabelled antibodies in the diagnosis of cancer.
7. CT Scan versus PET scan for Lung cancer.
8. Differenital diagnosis of retroperitoneal lump in a 25 years old male.
9. Molecular biology of breast cancer.
10.Treatment of recurrent head and neck cancer.
August 2009 :
I. Essays: 2 x 20 = 40
1. WHO classification of ovarian tumors and role of neoadjuvant and adjuvant chemo therapy in epithelial tumors of ovary.
2. Diagnosis, staging and non surgical management of carcinoma of oesophagus.
II. Write short notes on: 10 x 6 = 60
1. Neuroblastoma.
2. Prostate cancer – staging and management.
3. Telemarase therapies.
4. Sorfenib.
5. Clinical utility of genetic testing.
6. Adjuvant therapy for early breast cancer.
7. Anaemia in multiple myeloma
8. Quality of life in breast cancer
9. Ewings sarcoma molecular biology.
10. Cancer vaccines.
August 2011 :
(180 Min)
Answer ALL questions in the same order. :
I. Elaborate on :
1. Discuss the mechanism of action and the clinical indications for Photodynamic therapy in detail.
2. Discuss the histological classification of epithelial tumors of Lung.
II. Write notes on :
1. Dietary carcinogens.
2. Molecular Imaging in Medical Oncology.
3. Inferior vena cava filters.
4. Endobronchial ultrasound.
5. Raloxifene.
6. Port site metastasis.
7. Lung cancer screening.
8. Biliary Drainage.
9. Single Nucleiotide Polymorphism.
10. Cryptorchidism.
August 2012 :
I. Elaborate on: Pages Time Marks
1. Discuss in detail Fertility Preservation Strategies in current Oncology Practice.
2. Discuss in detail the current role of a pathologist in the diagnosis and prognostication of Lung Carcinoma.
II. Write notes on :
1. Role of Nuclear Medicine Physician in Cancer Pain Management.
2. Transfusion Associated GVHD.
3. Epigenetics and Clinical Relevance in Oncology.
4. Indications of PET CT imaging in Gastro Intestinal Tumours.
5. Radio immune conjugates in Management of Lymphomas.
6. Indications and relevance of Magnetic Resonance Imaging of the Breast.
7. Indian scenario in screening of Carcinoma Cervix.
8. Tamoxifen in Chemoprevention.
9. Paraneoplastic Manifestations in Lung Carcinoma.
10. Approach to Stage II Breast Carcinoma diagnosed in 2nd Trimester of Pregnancy.
August 2013 :
I. Elaborate on :
1. Discuss the histo-pathological classification of ovarian cancers.
2. Discuss in detail Hereditary cancers, including the management of unaffected carriers of BRCA1 deleterious mutations.
II. Write notes on :
1. Differential diagnosis of small blue round cell tumours.
2. Grading of epithelial breast tumours.
3. Molecular basis, clinical features and management of Gastrointestinal stromal tumours.
4. Indications, contraindications and basic principles of Radio-labelled monoclonal antibodies.
5. Management of the Retroperitoneal tumours.
6. Diagnostic workup of Acute lymphoblastic leukaemia.
7. Radio-isotopes useful in PET-CT and oncological applications of PET-CT.
8. Zero order versus first order kinetics in cancer therapy.
9. Parasites causing cancers.
10. Magnetic resonance imaging of the breast.
August 2014 :
I. Elaborate on :
1. Role of PET-CT scan in diagnosis, assessing response and treatment of Lymphomas.
2. Discuss the differential diagnosis and management of a 30 yr old male with Superior Vena caval Syndrome.
II. Write notes on :
1. Management of liver metastases by interventional radiology.
2. Use of photodynamic therapy in treatment of cancer.
3. Epidermal Growth Factor Receptor Inhibitors in Non-Small cell Lung cancer
4. Risk Stratification and treatment recommendations of GIST.
5. Chemo radiation in locally advanced cancer Esophagus.
6. Enumerate the different staging system in Gastric cancer and their clinical implications.
7. Poor prognosis Estrogen Receptor-positive breast cancer.
8. Circulating tumor cells and their utility in management and outcomes.
9. Denosumab – mechanism of action, dose, advantages in management of bone metastases.
10. Thyroid cancer-Emerging role for targeted therapies