Name of the University : The Tamilnadu Dr. M.G.R. Medical University
Degree : M.S.
Branch : Branch III –Ophthalmology
Subject Code/Name : 2225/Applied Basic Sciences In Ophthalmology
Paper : I
Document Type : Question Bank
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TNMGRMU Applied Basic Sciences in Ophthalmology
September 2008 :
Sub. Code: 2225
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M.S. DEGREE EXAMINATION
Branch III –Ophthalmology
Paper I – APPLIED BASIC SCIENCES IN OPHTHALMOLOGY
(For candidates admitted from 2004-2005 onwards)
Q.P. Code : 222225
Time : Three hours
Maximum : 100 marks
All questions carry equal marks. :
I. ANATOMY – Answer any FOUR : (4 X 5 = 20)
1. Development of eye.
2. Corneal endothelium.
3. Retina.
4. Superior orbital fissure.
5. Angle of Anterior Chamber.
II. PHYSIOLOGY – Answer any FOUR : (4 X 5 = 20)
1. Blood Aqueous Barrier.
2. EOG.
3. Corneal endothelial pump.
4. Optics of contact lens.
5. Visual pathways.
III. BIOCHEMISTRY– Answer any THREE : (3 X 5 = 15)
1. Immunoglobulins in tear.
2. Biochemical changes in Diabetic Retinopathy.
3. Lenticular metabolism.
4. Glycosylated Haemoglobin Test.
IV. MICROBIOLOGY – Answer any THREE : (3 X 5 = 15)
1. Pseudomonas.
2. Herpes zoster.
3. Grams stain.
4. Aspergillosis.
V. PHARMACOLOGY– Answer any THREE : (3 X 5 = 15)
1. Viscoelastic substances.
2. Perfluoropropane.
3. Silicon oil.
4. Anti VEGI (Vascular endothelial Growth factor).
V1. PATHOLOGY– Answer any THREE : (3 X 5 = 15)
1. Pathology of toxoplasma retinitis.
2. Pathology of Retinoblastoma.
3. Conjunctival cyst.
4. Corneal Degenerations.
March 2009
I. ANATOMY – Answer any FOUR : (4 x 5 = 20)
1. Development of retina.
2. Blood supply of optic nerve head.
3. Relations of cavernous sinus.
4. Visual pathway.
5. Angle of anterior chamber.
II. PHYSIOLOGY – Answer any FOUR : (4 x 5 = 20)
1. Theories of color vision.
2. Electro oculogram.
3. Pupillary reflexes.
4. Dynamics of aqueous formation.
5. Binocular single vision.
III. BIOCHEMISTRY– Answer any THREE : (3 x 5 = 15)
1. Metabolism of vitreous.
2. Anaerobic glucose metabolism.
3. Walds visual cycle.
4. Biochemical changes during.
IV. MICROBIOLOGY – Answer any THREE : (3 x 5 = 15)
1. Chlamydia trachomatis.
2. Human immuno deficiency virus.
3. Hypersensitivity in Eye.
4. Diphtheria bacillus.
V. PHARMACOLOGY– Answer any THREE : (3 x 5 = 15)
1. Anti fungal drugs.
2. Immuno suppressive drugs (immuno suppressive drugs).
3. Vitreous substitutes.
4. Anti metabolites.
V1. PATHOLOGY– Answer any THREE : (3 x 5 = 15)
1. Histopathology of malignant melanoma.
2. pathological features of endophthalmitis.
3. Dalen fuchs nodules.
4. Vascular changes in diabetic retinopathy.
September 2009
I. ANATOMY – Answer any FOUR : (4 x 5 = 20)
1. Ciliary body and muscle.
2. Cavernous sinus.
3. Angle of anterior chamber
4. Anatomy of lid.
5. Orbital spaces.
II. PHYSIOLOGY – Answer any FOUR : (4 x 5 = 20)
1. Theories of color vision.
2. Pupillary reactions and pathway.
3. Blood aqueous barrier.
4. Maintenance of corneal transparency.
5. Lacrimal secretion and drainage.
III. BIOCHEMISTRY– Answer any THREE : (3 x 5 = 15)
1. Photochemistry of vision.
2. Metabolic lipid disorders.
3. Pathogenesis of cataract in diabetics.
4. Amino acid – normal and abnormal metabolism.
IV. MICROBIOLOGY – Answer any THREE : (3 x 5 = 15)
1. Cytomegalo virus.
2. Cysticercosis.
3. Toxoplasmosis.
4. Hypersensitivity reactions.
V. PHARMACOLOGY– Answer any THREE : (3 x 5 = 15)
1. ß – blockers
2. Tear substitutes.
3. Drug delivery techniques
4. Anti fungals.
V1. PATHOLOGY– Answer any THREE : (3 x 5 = 15)
1. Basal cell carcinoma.
2. Proliferative retinopathy.
3. Stromal dystrophies.
4. HLA-B27 uveitis.
March 2010
I. ANATOMY (4 x 5 = 20)
1. Optic foramen.
2. Anatomy of the cornea.
3. Development of the eye.
4. Blood supply to the eye.
II. PHYSIOLOGY (4 x 5 = 20)
1. Aqueous humour dynamics.
2. Physiology of the vision.
3. Pupillary reflex.
4. Theories of colour vision.
III. BIOCHEMISTRY (3 x 5 = 15)
1. Ocular metabolism.
2. Lipid profile.
3. Photopic vision.
IV. MICROBIOLOGY (3 x 5 = 15)
1. Gonococcus.
2. Hydatid cyst.
3. Chlamydia trachomatis.
V. PHARMACOLOGY (3 x 5 = 15)
1. Lignocaine.
2. Sympathomimetic drugs.
3. Rose Bengal.
V1. PATHOLOGY (3 x 5 = 15)
1. Arcus senilis.
2. Pathogenesis of uveitis.
3. Pathology of malignant melanoma.
September 2010
I. Anatomy :
1. Anatomy of Optic nerve.
2. Anatomy of Human lens.
3. Development of the eye.
4. Ciliary body.
II. Physiology :
1. Lacrimal secretion.
2. Physiology of Binocular vision.
3. Pupillary reactions and pathway.
4. Physiology of accommodation.
III. Biochemistry :
1. Biochemical changes in cataract.
2. Disorders of Lipid metabolism.
3. Photochemistry of vision.
IV. Microbiology :
1. Retrovirus.
2. Hypersensitivity reactions.
3. Herpes Simplex.
V. Pharmacology :
1. Antifungal drugs for ophthalmic use.
2. Cyclosporine.
3. 5-Fluorouracil.
V1. Pathology :
1. Kaposi’s sarcoma.
2. Pathogenesis of uveitis.
3. Retinoblastoma.
May 2011
I. Anatomy :
1. Anatomy of superior orbital fissure.
2. The nerve supply and actions of the recti and oblique muscles of the eyeball.
3. Central retinal artery.
4. Development of human lens.
II. Physiology :
1. Theories of accommodation.
2. Lacrimal secretion and tear film layer.
3. Scotopic vision.
4. Electro Oculogram (EOG).
III. Biochemistry :
1. Walds visual cycle.
2. Composition of vitreous humour.
3. Free radical damage.
IV. Microbiology :
1. Cysticercus.
2. Laboratory diagnosis of AIDS.
3. Candidiasis.
V. Pharmacology :
1. ACE (Angiotensin Converting Enzyme) inhibitors.
2. Vitreous substitutes.
3. Cycloplegics.
VI. Pathology :
1. Pathology of Retinoblastoma.
2. Suppurative endophthalmitis.
3. Siderosis bulbi.