Organisation : Central Board of Secondary Education (CBSE)
Class Name : 12th/HSC (Class XII)
Subject : Biotechnology
Download : Sample Question Paper 2024-25
Website : https://cbseacademic.nic.in//SQP_CLASSXII_2024-25.html
CBSE Class XII Biotechnology Sample Question Paper
Q. No. 1 to 12 are multiple choice questions. Only one of the choices is correct. Select and write the correct choice as well as the answer to these questions.
Related / Similar Question Paper : CBSE Class XII Biology Sample Question Paper 2024-25
1. An approach that utilises analysis of genome present in different environment to screen presence of variety of molecules.
A. Metagenomics
B. Proteomics
C. Strain preservation
D. Mutant selection
2. In animal cell culture, the CO2 levels in the incubator is usually maintained at-
A. 1-2%
B. 3-4%
C. 5-10%
D. 11-15%
3. Even if we know where the genes are in each genome, it’s difficult to count them due to:
(i) splice variants
(ii) overlapping genes
(iii) Post – trancriptional events
(iv) Mutations
A. (i), (iii)
B. (i), (ii)
C. (iii), (iv)
D. (ii), (iv)
4. Avocado growers in Kerela want to find a way to genetically engineer their crop to prevent it from ripening during shipping. This can be achieved by introducing-
A. genes for carotenoid biosynthesis.
B. gene from Bacillus amyloliquefaciens.
C. ethylene forming gene(s).
D. gene for protein containing sulphur rich amino acids.
5. Microbial species used for commercial production of citric acid is-
A. Saccharomyces cerevisiae
B. Aspergillus niger
C. Streptomyces griseus
D. Aspergillus oryzae
6. To reduce the possibility of religation of vector without picking insert, the
following method or methods may be used-
(i) Use of DNA Ligase
(ii) Use of Alkaline Phosphatase
(iii) Use of two different Restriction enzymes for cloning
(iv) Hybridoma technology Select the correct answer from options below
A. (i), (iv)
B. (ii), (iii)
C. (iii), (iv)
D. (ii), (iv)
7. In a comparative cDNA microarray, the cDNA obtained from the normal and diseased cells are labelled with red and green fluorescent dyes respectively. The yellow colour of the spot indicates-
A. Gene is expressed only in normal cells.
B. Gene is not expressed either in normal cells or in diseased cells.
C. Gene expressed only in diseased cells.
D. Gene expressed in equal measure in both types of cells.
8. Which disease has its locus on chromosome no 1 and 6?
A. Huntington’s disease
B. Migraine
C. Alzheimer’s disease
D. Cystic fibrosis
9. A molecular disease which leads to increased hydrophobic interactions within the haemoglobin protein is-
A. Thalassemia
B. Sickle Cell anaemia
C. Mad Cow
D. SCID
10. Interleukin-2 produced using CHO cell line is used for-
A. anaemia therapy.
B. cancer therapy.
C. stroke.
D. treatment of autoimmune disease.
11. Proteome of a given cell is dynamic because:
A. In response to internal and external changes the biochemical machinery of the cell could be changed.
B. In response to internal and external changes the biochemical machinery of the cell could not be changed.
C. No direct relationship exists between internal and external changes in the biochemical machinery of the cell.
D. Indirect relationship exists between internal and external in changes the biochemical machinery of the cell.
12. A novel gene that codes for the epitope has been introduced into yeast cells to produce-
A. Hepatitis B Vaccine
B. Subtilisin
C. EPO
D. tPA
General Instructions:
(i) All questions are compulsory.
(ii) The question paper has five sections and 33 questions.
(iii) Section–A contains 12 Multiple choice questions and 4 Assertion-Reasoning based questions of 1 mark each; Section–B has 5 short answer questions of 2 marks each; Section –C has 7 short answer questions of 3 marks each; Section-D has two case-based question of 4 marks; Section-E has three long answer questions of 5 marks each.
(iv) There is no overall choice. However, internal choices have been provided in some questions. A student has to attempt only one of the alternatives in such questions.
(v) Wherever necessary, neat and properly labeled diagrams should be drawn.
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