Name of the College: RajaRajeshwari Medical College & Hospital
University : Rajiv Gandhi University of Health Sciences
Degree : MBBS
Subject Name : Biochemistry
Document Type : Question Bank
Website : college.rrmch.org
Download Model/Sample Question Paper :
Jan 2008 to Dec 2013 : https://www.pdfquestion.in/uploads/college.rrmch.org/4248-UG-Biochemistry-QP-Jan-2008-Dec-2013.pdf
Biochemistry MBBS Question :
M.B.B.S. PHASE – I Degree Examination . August 2007
[Max. Marks: 90]
Biochemistry [Old Scheme]
Related / Similar Question Bank :
Pharmacology Important Questions For MBBS Pdf
QP Code – 1005
Your answers should be specific to the questions asked. :
Draw neat labeled diagrams wherever necessary. :
LONG ESSAY : 2 X 10 = 20 Marks
1. Write the reactions of Krebs’s citric acid cycle. Write the significance of the pathway.
2. Define genetic code. What are the salient features of genetic code?
SHORT ESSAY :
3. Protein energy malnutrition
4. Malate-aspartate shuttle
5. Pyruvate-dehydrogenase complex
6. Tumor markers
7. Functions of plasma proteins
8. Lac operon
9. Plasma buffers
10. Formation and utilization of ketone bodies
11. Competitive inhibition
12. Fluid mosaic model of plasma membrane .
10 X 5 = 50 M§rks
SHORT ANSWERS :
13. Uncouplersof oxidative phosphorylation
14. Zymogens
15. Ninhydrin reaction
16. Lysosomes
18. Write the defect in the following diseases
a) Alkaptonuria
b) Maple syrup urine disease
c) Classical albinism
d) Hartnup’s disease
19. Rate limiting reaction in pyrtmtdrneblosvnthesis .
20. Role of bile salts in digestion
21. Beer-Lambert’s law
BIOCHEMISTRY : (Revised Scheme II)
Your answer shall be specific to question asked. Draw neat and labelled diagrams wherever necessary. Use separate answer books for section A and section B.
LONGESSAY : 1 X 10 = 10 Marks
1. Define Isoenzymes. Mention the principles used for separation of Isoenzymes. Write about the clinical importance of Isoenzymes
SHORT ESSAY : 5 X 5 = 25 Marks
2. List the important products formed from Tyrosine and write the metabolic pathways leading to the formation of any two of them
3. Mechanisms of action of Glucagon
4. Single electron carrier components of respiratory chain
5. Mechanism of pyruvate dehydrogenase enzyme action and it’s biochemical importance
6. List various types of fatty acid oxidation. Write about activation of fatty acids for oxidation
SHORT ANSWERS :
7. Functions of plasma membrane
8. Lipid peroxidation – clinical importance
9. Role of growth factors in carcinogenesis
10. Glucose 6 phosphate dehydrogenase deficiency
11. Functional Classification of proteins
5 X 3 = 15 Marks
QP Code: 1080 – Paper II (Max, Marks: 50)
Use separate answer book
LONG ESSAY : 1 X 10 = 10 Marks
1. What is the importance of maintaining acid-base balance in the body? Write in detail how kidney helps in maintaining acid-base balance
SHORT ESSAY : 5 X 5 = 25 Marks
2. Replication of lagging strand
3. List metabolic functions of Ascorbic acid. How do you detect it’s defiCiency? What is the daily requirement?
4. BMR(Basal Metabolic rate)
5. Degradation of Heme
6. Gene therapy
SHORT ANSWERS :
7. Iodine metabolism
8. Importance of base pairing
9. Molecular defect in and consequences of sickle cell disease
10. Sources and beneficial effects of dietary fiber
11. What is reference range? How is it calculated?
Biochemistry (Revised Scheme) :
Your answers should be specific to the questions asked. Draw neat labeled diagrams wherever necessary.
Long Essay : 2 X 9 = 18 Marks
1. Give an account of the metabolism of glycine and outline the synthesis of different important substances from glycine
2. Give an account of the f3-oxidation of palmitic acid and its energetics
Short Essay :
3. Glycogenesis
4. Metabolism of galactose
5. Competitive inhibition and its usefulness in therapeutics
6. Multienzyme complexes
7. Biochemical functions of vitamin C
8. One carbon metabolism
9. Fatty livers and lipotropic factors
10. Gout
11. Replications
12. Calcium homeostasis
Short Answers :
13. What are epimers? Give examples
14. Isoelectric pH and its significance
15. Essential fatty acids
16. Give two examples of substrate level phosphorylation
17. How is aspirin detoxified?
18. Name two metabolic disorders of amino acids metabolism and indicate the enzyme defect
19. Name two lipid storage disorders and indicate the corresponding enzyme defect
20. Indicate sources of various atoms of purine ring
21. Name the hemoglobinopathies
22. What is a codon? Mention the termination codons
23. Give two examples for post translational modification
24. How is heme synthesis regulated?
25. Outline the structure of immunoglobulins
26. Name four liver function tests
27. SDA
28. Nutritional deficiency disorders in India
M.B.B.S. PHASE – I Degree Examination – January 2008 :
Biochemistry : [Old Scheme]
QP Code – 1005
Your answers should be specific to the questions asked. Draw neat labeled diagrams wherever necessary.
Long Essay : 2 X 10 = 20 Marks
1. What is Normal blood glucose level? Describe the various mechanisms for its regulation
2. What is Lac-operon? Describe the steps of protein biosynthesis
Short Essay :
3. Functions of folic acid and vit B12
4. Ketosis
5. Importance of HMPpathway
6. Urea cycle
7. Formation and functions of glycine
8. Creatine – phosphate
9. Clinical significance of enzymes
10. Blood buffers
11. Formation and fate of bilirubin
12. Applications of recombinant DNA technology
Short answers :
13. Name the liver function tests based on enzyme measurement
14. What is allosteric modification of enzyme? Give two examples
15. Define creatinine clearance. What is the normal value?
16. Differentiate between ICF and ECF
17. Write the important metabolites derived from tryptophan
18. Inhibitors of respiratory chain
19. What is glycosylated hemoglobin? Write its importance
20. Four functions of plasma proteins
21. What is normal blood urea level? Two causes of uremia
22. Name the various bonds stabilizing protein structure