Name of the University : Alagappa University
Degree : M.Sc
Department : Biology
Subject Code/Name :Immunobiology
Document Type : Model Question Papers
Website : alagappauniversity.ac.in
Download Model/Sample Question Paper : April 2011 :https://www.pdfquestion.in/uploads/alagappauniversity.ac.in/4174.-M.Sc.,%20Biotechnology.pdf
Alagappa Immunobiology Question Paper
M.Sc. DEGREE EXAMINATION, APRIL 2011
Time : 3 Hours
Maximum : 75 Marks
Part A (10 × 2 = 20)
Related : Alagappa University Research Methodology And Basic Of Nanoscience M.Phil Model Question Papers : www.pdfquestion.in/4136.html
Answer all questions.
1. Clonal Selection theory.
2. – -lymphocyte markers.
3. Adjuvants with example.
4. Super antigens.
5. Anaphylatoxins.
6. Hashmito’s thyroiditis.
7. MHC halotypes.
8. Isograft Vs Allograft.
9. Oncogenes with example.
10. Edible Vaccines.
11. (a) Give a short account on Cancer Immunotherapy.
(b) Differentiate Type – I and Type II hypersensitivity reaction.
12. (a) Describe class I and Class II MHC molecules.
(b) Explain the mechanism of combating infection
13. (a) Explain the mechanism involved in phagocytosis.
(b) Explain the various types of immunization.
14. (a) What are the factors that favour antigen-antibody
(b) Write notes on :(i) Hapten.(ii) Epitope.
15. (a) Explain the lymphoid organs and their role in immune system.
(b) Comment on cell mediated immunity.
16. Describe in detail the immunology of AIDS.
17. Explain in detail on Auto immune disorder.
18. Compare Classical and alternative pathway.
19. Describe the structure and functions of various
20. Write note on the following :—(i) CD markers (2)
Recombinant DNA Technology
M.Sc. DEGREE EXAMINATION, APRIL 2011
Time : 3 Hours Maximum : 75 Marks
Part A (10 × 2 = 20)
Answer all questions.
All questions carry equal marks.
1. Write DNA dependent RNA polymerases.
2. Define Ribozymes.
3. What is HACs –
4. Write the advantages of eukaryotic vectors –
5. Define adapters and linkers.
6. Write down the methods of selection of clone.
7. Write about nested PCR.
8. Write about Zoo blot.
9. What is Cystic fibrosis –
10. Write the steps involved in purification of proteins.
11. (a) Write down the mechanisms involved in DNA
(b) Write note on :(i) Exo III nuclease.(ii) T7 DNA polymerase.
12. (a) Write a note on gene fusion vectors with examples.
(b) Describe about advantages and disadvantages of
13. (a) Write down the immunological screening
(b) Briefly explain about cloning strategies.
14. (a) Write the principles of pyrosequencing.
(b) Write a note on DNA footprinting.
15. (a) Explain any one commercial enzyme produced
(b) Discuss about the Human genome projects.
16. Define Restriction endonucleases and explain the
17. Write down the applications of the cosmid, lambda
18. How to construct genomic DNA libraries through
19. Explain PCR based site – directed mutagenesis.
20. Explain the methods of production and purification of
recombinant Hepatitis B vaccine.
Plant Molecular Biology
(CBCS—2008 onwards)
Time : 3 Hours
Maximum : 75 Marks
Part A (10 × 2 = 20)
Answer all questions.
All questions carry equal marks Explain
1. Biodegradable plastics
2. Homoplastomic and Heteroplastomic plants.
3. Signal peptides.
4. Promiscous DNA
5. Binary vector.
7. Vir genes.
8. Illegitimate recombination.
9. Gene silencing
10. Transposons
Part B (5 × 5 = 25)
Answer all questions, choosing either (a) or (b)
All questions carry equal marks
11. (a) Comment on the organisation of chloroplast genome.
(Or)
(b) Explain the essential regions of plant expression vectors with example
12. (a) How do we identify the intra species variations using PCR based markers?
(Or)
(b) Explain the molecular mechanism involved in T-DNA integration to plant genome.
13. (a) What are the strategies adopted for vaccine production in plants?
(Or)
(b) Discuss the different cryopreservation techniques.
14. (a) Explain the multistep process of protein folding in plants.
(Or)
(b) Discuss the role of some important genes involved in drought tolerance.
15. (a) Discuss about Artificial seed and comment on its applications.
(Or)
(b) Explain the structure of chromatin with illustration.
Part C (3 × 10 = 30)
Answer any three questions
All questions carry equal marks
16. How the molecular markers are used in the plant improvement ?
17. Explain ethylene’s role in fruit ripening and genes involved in the process
18. Write short notes on:
(a) Virus mediated gene transfer,
(b) Microinjection,
(c) Electroporation,
(d) Particle gun method
19. Explain
(a) Selectable markers,
(b) Reporter genes and
(c) Inducible promoters.
20. Comment on :
(a) Abiotic stress tolerance
(b) Herbicide tolerance
(c) Insect resistance