Name of the University : The Tamilnadu Dr. M.G.R. Medical University
Degree : M.Sc Non Medical Degree Examination
Subject Code/Name : 3001/Principles of Epidemiology & Biostatistics
Paper : I
Document Type : Question Bank
Website : web.tnmgrmu.ac.in
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Principles of Epidemiology & Biostatistics :
MAY 2011 :
[KY 234]
Sub. Code: 3001
Related : TNMGRMU Epidemiology, Biostatistic & Entomology M.Sc Non Medical Question Bank : www.pdfquestion.in/4042.html
M.Sc. (EPIDEMIOLOGY) DEGREE EXAMINATION.
Part I :
Paper I : PRINCIPLES OF EPIDEMIOLOGY AND BIOSTATISTICS
Q.P. Code : 313001
Time : Three hours
Maximum : 100 marks
Answer All questions. :
I. Elaborate on : (2 x 20 = 40)
1. What are the differences between Observational studies and experimental studies? Explain analysis of a cohort study with a suitable example.
2. When do we use ANOVA one-way and Two-way tests and what are the assumptions? Explain ANOVA one-way with an example.
II. Write notes on : (10 x 6 = 60)
1. Selection of Controls in a case-control study
2. Bradford Hill’s criteria for causality
3. Internal and external validity
4. Health economics and Cost benefit analysis
5. Correlation coefficient
6. Direct standardization
7. Life tables
8. Laws of probability
9. Cluster sample
10. Environmental Pollution & methods of prevention.
October 2011 :
I. Elaborate on :
1. What are Observational studies? Name some of the important observational studies and describe in detail a Case-Control study with an example.
2. Explain the concept of tests of significance, the underlying assumptions and the interpretation of p-value. What are Type 1 and Type 2 errors? How would you increase the Power of the test for a given Type1 error?
II. Write notes on :
1. Ecological studies and ecological fallacy
2. Randomization in Clinical Trials
3. Immunogenicity
4. Attributable risk and etiologic fraction
5. Measures of cost-effectiveness
6. Indirect standardization
7. Logistic regression
8. Non Parametric Tests
9. Sensitivity analysis
10. Secular Trend
Sub. Code: 3001
I. Elaborate on:
1. Explain Cohort and Case Control Study Design and its relevant Measures of association with simple example.
2. a. Explain the measures of central tendency and dispersion.
b. Write a brief note on Types of Probability Sampling.
II. Write notes on:
1. Explain Incidence and Prevalence.
2. Write a note on Sensitivity, Specificity, Predictive values, likelihood ratios and ROC.
3. Name the types of experimental study designs and explain with simple examples.
4. Write a brief note on Epidemiology of diseases of national importance including National Programmes
a) Diarrhea
b) Sexually Transmitted Diseases
c) Malnutrition
5. Explain the Natural history of disease.
6. Briefly explain probability distribution.
7. Write a brief note on Survival Analysis.
8. Explain the demographic transition.
9. What are the factors affecting fertility.
10. Write a note on prevention of environmental pollution.
May 2012 :
I. Elaborate on :
1. Discuss different methods of Validity and Reliability.
2. Discuss Construction of Life table and its uses.
II. Write notes on :
1. Incidence and prevalence.
2. Modified deterministic model.
3. Field trails.
4. Relative risk for cohort study.
5. Time Series Analysis.
6. Differences between standard deviation and standard error.
7. Systematic Random Sampling.
8. Assumptions of Analysis of Variance.
9. General Fertility Rate.
10. Epidemiology of road traffic accidents.
October 2012 :
I. Elaborate on : Pages Time Marks
1. Discuss different methods of Validity and Reliability.
2. Discuss Construction of Life table and its uses.
II. Write notes on :
1. Incidence and prevalence.
2. Modified deterministic model.
3. Field trails.
4. Relative risk for cohort study.
5. Time Series Analysis.
6. Differences between standard deviation and standard error.
7. Systematic Random Sampling.
8. Assumptions of Analysis of Variance.
9. General Fertility Rate.
10. Epidemiology of road traffic accidents.
April 2013 :
I. Elaborate on :
1. Define sampling. Discuss the various sampling methods with its merits and demerits.
2. A leading drug company has introduced a new vaccine to prevent cervical cancer. How will you design a Randomized Controlled Study to measure the effectiveness of the vaccine.
II. Write notes on :
1. Gantt chart
2. Advantages and disadvantages of a Case control study
3. Life table and its uses
4. Advantages and disadvantages of non parametric test
5. Scale of measurement
6. Principles of sample size calculation
7. Time trends in disease occurrence
8. Time series analysis
9. Uses of epidemiology
10. Relative risk and attributable risk
October 2013 :
I. Elaborate on :
1. Discuss various methods of Observational study designs.
2. Discuss Normal, Binomial and Poisson distributions.
II. Write notes on :
1. Measures of mortality.
2. Likelihood ratio in diagnostic test.
3. Decision tree.
4. Vaccine preventable diseases.
5. Coefficient of variation.
6. Confidence interval.
7. Differences between parametric and non parametric test.
8. Log linear models.
9. Gross Reproduction Rate.
10. Injury control in working environment.