Name of the University : The Tamilnadu Dr. M.G.R. Medical University
Degree : M.Sc Non Medical Degree Examination
Subject Code/Name : 4033/Physics of Nuclear Medicine And Internal Dosimetry
Year : II
Paper : III
Document Type : Question Bank
Website : web.tnmgrmu.ac.in
Download Model/Sample Question Paper :
2012-2013 : https://www.pdfquestion.in/uploads/web.tnmgrmu.ac.in/4036-284033KY.pdf
Physics of Nuclear Medicine & Internal Dosimetry :
Sub. Code: 4033
M.Sc (MEDICAL PHYSICS) DEGREE EXAMINATION- MAY 2012
SECOND YEAR
Related : TNMGRMU Advanced Techniques of Radiotherapy M.Sc Non Medical Question Bank : www.pdfquestion.in/4035.html
PAPER III – PHYSICS OF NUCLEAR MEDICINE AND INTERNAL DOSIMETRY
Q.P. Code: 284033
Time: Three hours Maximum: 100marks
180 (Min)
Answer All questions. :
I. Elaborate on :
1. What is two compartmental model? Describe two compartmental model with and without back transference.
2. Write in detail about PET detector and scanner design.
II. Write notes on:
1. Accelerator based radionuclides.
2. Photonuclear activation.
3. Life span of RBC.
4. Pinhole collimator.
5. Three dimensional imaging techniques.
6. Single Photon Emission Computed Tomography.
7. Working of medical cyclotron.
8. Positron emitting radionuclides.
9. Dose reciprocity theorem.
10. Treatment of thyroid cancer with 131I.
APRIL 2013 :
I. Elaborate on: (2X20=40)
1. Describe in detail about the construction and function of a gamma camera
2. Discuss the principle of coincidence detection and explain the application of PET scan in medicine and advantage over gamma camera.
II. Write notes on: (10X6=60)
1. Spatial resolution, Temporal resolution
2. Medically useful radionuclide produced by cyclotron
3. Pulse height analyzer
4. Difference between static and dynamic gamma imaging
5. Desirable properties required for gamma imaging radionuclide and radiopharmaceutical.
6. Function of collimator and types of collimator
7. Define: Physical half-life, biological and effective half-life of a radionuclide and establish relationship between them
8. Radiation safety procedures for personnel and patient during radionuclide administration.
9. Positron emission tomography
10. Technetium generator
OCTOBER 2013 :
I. Elaborate on: (2X20=40)
1. Describe in detail about the three methods for producing nuclear medicine radionuclides.
2. Discuss about principles of operation of single photon emission tomography
II. Write notes on: (10X6=60)
1. Internal dosimetry and discuss about MIRD method.
2. Contrast and resolution
3. Coincidence detection
4. Image reconstruction and image quality.
5. Attenuation correction and scatter correction.
6. Calculate the total energy production and energy of each photon during annihilation processes.
7. Dead time, field of view and field uniformity
8. PET detector materials
9. Radiation synovectomy and its isotopes.
10. Waste disposal methods used in nuclear medicine laboratory.
Physics of Radiation Therapy :
I. Elaborate on :
1. Explain the detail the design and working of a medical linear accelerator.
2. Describe the acceptance, commissioning and quality assurance protocol for installing a remote after loading equipment.
II. Write notes on :
1. Drive the relationship between Tissue Maximum Radio and Percentage Depth Dose.
2. How a integrated brachytherapy facility works. Give the sequence of procedures that is followed in such facilities.
3. Describe the construction of travelling and standing wave guides.
4. Describe the construction and working of a Van De Graff generator.
5. A patient has to receive 250cGy by rotation therapy using 4 MV X-rays. The field size is 6×10 sq.cm. at the isocenter which is at 100cms. The average TMR is 0.756, Machine output is 200 MU/min, collimator scatter factor for the given field size is 0.98 and phantom scatter is 0.99. Find the number of monitoring units required to deliver the treatment.
6. Explain the how the skin sparing effect is achieved by the high energy photon beams.
7. Describe the dose and volume specification for reporting gynecological treatments using ICRU 38 protocol.
8. Describe the setup for measuring the back scatter factor and peak scatter factor.
9. Describe the dose volume histograms and conformity indices used for studying the merits of a treatment plan.
10.Explain the Clarkson’s method used for calculation the irregular treatment field.
APRIL 2013 :
I. Elaborate on :
1. Describe the output calibration of high energy teletherapy Unit on the basis of IAEA TRS 398 protocol.
2. Describe the various beam modifying and shaping devices And its clinical importances.
II. Write notes on :
1. Describe the Virtual Simulations.
2. Describe the asymmetric collimations.
3. Describe the travelling and standing wave guide.
4. Describe the Field analyser.
5. Describe the Dynamic Wedges.
6. Explain the ICRU 50.
7. Describe the electron dosimetry.
8. Explain the neutron capture therapy.
9. Describe the significance of Percentage Depth dose And Tissue Maximum, ratio.
10. Describe the cyclotron