Name of the University : The Tamilnadu Dr. M.G.R. Medical University
Degree : PG Diploma in Diabetology (D.DIAB.)
Subject Code/Name : 3071 Applied Basic Medical Sciences
Paper : I
Document Type : Question Bank
Website : web.tnmgrmu.ac.in
Download Model/Sample Question Paper :
1998-2000 : https://www.pdfquestion.in/uploads/we…7-343071KC.pdf
2001-2013 : https://www.pdfquestion.in/uploads/we…7-343071KX.pdf
Applied Basic Medical Sciences :
March -2009 :
I. Essay questions : (2 X 20 = 40)
1. Insulin resistance : Definition, Mechanisms, it’s assessment and consequences of insulin resistance.
2. Pathogenesis of Chronic complications of diabetes mellitus.
II. Write short notes on : (10 X 6 = 60)
1. Auto immunity and diabetes.
2. Visceral Fat.
3. Threfty gene hypothesis.
4. Glucagon and it’s role in diabetes.
5. Incretin effect.
6. AMP Kinase.
7. Wollfram’s syndrome.
8. Non invasive glucose monitoring.
9. Genetic beta-cell defects.
10. C-Peptide.
April 2011 :
I. Elaborate on :
1. Describe the Mechanism and pathophysiology of Microvascular complications of diabetes and discuss the options for interventions.
2. Explain and discuss in detail the role and mechanism of insulin resistance in the pathogenesis of Type II Diabetes mellitus.
II. Write notes on :
1. Morphologial features of islets of langerhans.
2. Incretin effect.
3. Mechanism of action of Glitazones.
4. Stem cell therapy in Diabetes.
5. Neonatal Diabetes.
6. NAFLD – Non alcoholic fatty liver disease.
7. IGF – I – Insulin like growth factor.
8. Adiponectin.
9. Dapagliflozin.
10. Glucotoxicity.
April 2012 :
I. Elaborate on :
1. Discuss the Immunology and Pathogenesis of Type 1 Diabetes. 16 35 15
2. Describe the Lipid metabolism in normal and diabetes persons and the pathophysiology of dyslipidaemia in Type 1 and Type 2 Diabetes. 16 35 15
II. Write notes on :
1. Anatomy of the Islets of Langerhans.
2. Entero Insular Axis.
3. Mechanism of action of Metformin.
4. Stem cell therapy in Diabetes.
5. Ketogenesis.
6. Polycystic ovarian syndrome.
7. Insulinoma.
8. Leptin.
9. Protein Kinase – C.
10. Actions of Glucagon Like Peptide-1.
April 2013 :
I. Elaborate on : (2X15=30)
1. Discuss the Insulin receptor and etiopathogenesis of insulin resistance.
2. Describe the metabolic changes during normal pregnancy and diabetic pregnancy.
II. Write notes on : (10X7=70)
1. Insulin Gene.
2. Incretins
3. Microalbuminuria
4. Classification of diabetes.
5. Thrifty genotype
6. Non Alcoholic Steato Hepatitis
7. Polyol pathway
8. Adiponectin
9. GLUT transporters
10. PPAR gene.
October 2013 :
I. Elaborate on : (2X15=30)
1. Discuss in detail about Homeostasis of Hepatic glucose output. Mention all about its regulation.
2. Discuss in detail about etio-pathogenesis of Ketone bodies production and their implication in blood. How will you detect ketone bodies in blood and urine.
II. Write notes on : (10X7=70)
1. Metabolic syndrome.
2. Glycosuria – Diabetic and non-Diabetic
3. Self Monitoring of Blood Glucose.
4. Islet cell antibodies.
5. Polyol pathway and its clinical implication.
6. Reverse cholesterol pathway.
7. Impaired glucose tolerance.
8. C-Peptide.
9. Animal models in Diabetes research.
10. Microscopic appearance of Diabetic Kidney disease.