Name of the University : Kerala University of Health Sciences
Degree : PG Degree Examinations in Pharmacology (MD)
Subject Name : General Pharmacological Principles and Applied Sciences
Paper : I & II
Year : May 2013
Document Type : Previous Question Paper
Website : kuhs.ac.in
Download Model/Sample Question Paper :
PAPER I : https://www.pdfquestion.in/uploads/kuhs.ac.in/3392-Paper%20I%20QP%20101112.pdf
PAPER II : https://www.pdfquestion.in/uploads/kuhs.ac.in/3392-Paper%20II%20QP%20102112.pdf
PAPER III : https://www.pdfquestion.in/uploads/kuhs.ac.in/3392-Paper%20III%20QP%20103112.pdf
PAPER IV : https://www.pdfquestion.in/uploads/kuhs.ac.in/3392-Paper%20IV%20QP%20104112.pdf
KUHS Pharmacology Previous Question Paper
PG Degree Examinations in Pharmacology (MD) – May 2013
Paper I : General Pharmacological Principles and Applied Sciences
Time: 3 hrs
Max marks:100
Answer all questions :
Draw diagrams wherever necessary :
Related : KUHS KUHS Basic Science Applied to Paediatrics MD Previous Question Paper : www.pdfquestion.in/3397.html
June 2013
Paper I
Essays: (20)
1. Explain the factors influencing drug action with examples and discuss the clinical relevance.
Short essays: (10×8=80)
2. Pharmacogenetics
3. Drug treatment in pediatric patients
4. Phase Ill clinical trials
5. Newer drug delivery systems
6. Drug regulation in India
7. Calcium channels
8. Transgenic animal models
9. Volume of distribution
Paper II
Experimental Pharmacology, Bioassay and Statistics
Time: 3 hrs
Max marks:100
Answer all questions :
Draw diagrams wherever necessary :
Essays: (20)
1. Discuss the evaluation of anti convulsant drugs.
Short essays: (8×10=80)
2. Null hypothesis.
3. Teratogenecity testing.
4. Four point assay.
5. Principles of bioassay.
6. Recombinant D.N.A technology.
7. Cumulative toxicity. 8. Generic drugs.
9. Animal screening of a drug molecule for its anti fertility effect.
Paper III
Clinical Pharmacology and Recent Advances
Time: 3 hrs
Max marks:100
Answer all questions
Draw diagrams wherever necessary
Essays: (20)
1. Discuss the recent advances in type II diabetes mellitus
Short essays: (8×10=80)
2. Treatment with neuraminidase inhibitors
3. SelectiveCOX-2COX-3inhibitors
4. Atypical anti depressants
5. Essential drug concept
6. Pharmaco economics
7. HPLC
8. Placebo.
9. Treatment of osteoporosis
Paper IV
Systematic Pharmacology, Chemotherapy and Therapeutics
Time: 3 hrs
Max marks:100
Answer all questions :
Draw diagrams wherever necessary :
Essays: (20)
1. Describe the mechanism of action, clinical uses and adverse effects of the anti neoplastic agents obtained from plant source.
Short essays: (8×10=80)
2. Insulin analogs
3. Liposomal amphotericin B
4. Potassium channel openers
5. Treatment of Alzheimer’s disease
6. Beta blockers in congestive heart failure
7. MOR tuberculosis
8. lmmunosuppressants
9. SSRls (selective serotonin reuptake inhibitors)
November 2016
Paper I
General Pharmacological Principles and Applied Sciences
Time: 3 hrs
Max marks:100
Answer all questions
Draw diagrams wherever necessary
Essays: (20)
1. Discuss the trans membrane receptor signalling mechanisms and explain drug action
Short essays: (8×10=80)
2. Drug dosing schedule in health and diseases
3. Structure activity relationship of phenothiazines
4. Pharmacogenetics
5. Teratogenicity
6. New drug delivery systems
7. Chronopharmacology
8. Explain drug interactions with suitable examples
9. PLASMA HALF LIFE
Paper II
Systematic Pharmacology, Chemotherapy and Therapeutics
Time: 3 hrs
Max marks:100
Answer all questions
Draw diagrams wherever necessary
Essays: (20)
1. Discuss in detail the current status in the treatment of hypertension.
Short essays: (8×10=80)
2. Pharmacotherapy of amoebiasis
3. Treatment of lepra reaction
4. Insulin analogues
5. Current guidelines in the treatment of angina
6. Third generation cephalosporins
7. Management of status epilepticus
8. Selective serotonin reuptake inhibitors (SSRI’s)
9. Non benzodiazepines and its uses
Paper III
Experimental Pharmacology, Bioassay and Statistics
Time: 3 hrs
Max marks:100
Answer all questions
Draw diagrams wherever necessary
Essays: (20)
1. Discuss experimental procedures used in evaluation of psychopharmacological drugs.
Short essays: (8×10=80)
2. ANOVA.
3. Transgenic animals.
4. Radio immunoassay.
5. Composition and functions of human ethics committee.
6. ELISA.
7. Bioavailability and bioequivalence studies.
8. Polymerase chain reaction.
9. Handling techniques of lab. animals – mice and rat.
Paper IV
Clinical Pharmacology and Recent Advances
Time: 3 hrs
Max marks:100
Answer all questions
Draw diagrams wherever necessary
Essays: (20)
1. Describe in detail the hormonal replacement therapy in therapeutics
Short essays: (8×10=80)
2. Rescue drugs in cancer chemotherapy
3. TDM( Therapeutic Drug Monitoring)
4. Biological response modifiers
5. Monoclonal antibodies
6. Immunosuppressants
7. Meta analysis
8. Spurious drugs.
9. Calcineurin inhibitors