Name of the University : GPAT India
Name of the Exam : GPAT Graduate Pharmacy Aptitude Test
Document Type : GPAT Model Paper
Website : http://gpatindia.com/free-gpat-niper-model-papers/
Download Sample Question Paper : https://www.pdfquestion.in/uploads/25200-GPATI.pdf
GPAT Graduate Pharmacy Aptitude Test Model Question Paper
** Here we provide latest information regarding GPAT-2018 & GPAT-2018 Test Series.Test Series will be conducted by Pharmacophore Solutions.
Related : Uttar Pradesh Technical University General Pharmacy B.Pharm Question Paper Model : www.pdfquestion.in/6173.html
Sample Questions
Physics
Q-1. This type of inhibition (In Red line) will called……………
(A) Noncomptitative
(B) Comptitative
(C) un Comptitative
(D)Mixed inhibition
Q-2. Which of the following ions may be effectively chelated by EDTA?
I. sodium II. lithium III. lead
(A) I only
(B) III only
(C) I and II only
(D) II and III only
Q-3. The term “impalpable” refers to a substance that is
(A) Bad tasting
(B) not perceptible to the touch
(C) greasy
(D) none
Q-4 Techniques used in the development of “biotechnological drugs” include
I. gene splicing
II. preparation of monoclonal antibodies
III. lyophilization
(A) I only
(B) III only
(C) I and II only
(D) II and III only
Q-5. Uses for surfactants in pharmaceutical products include
I. percutaneous absorption enhancers
II. cleansing agents
III. therapeutic activity
(A) I only
(B) III only
(C) I and II only
(D) I, II, and III
Q-6 High pressure and airless system to spray having pressure range
(A) 250-1000 Pisg
(B)400-2000 Pisg
(C)400-3000 Pisg
(D)250-3000 Pisg
Q-7 Poorly manufactured tablets may have small pinholes on the surface. This phenomenon is known as:
(A) Picking
(B) Mottling
(C) Leaching
(D) Cracking
Q-8 Creaming is a …………….. Process
(A) Irreversible
(B) reversible
(C) Difficult
(D) Both a &c
Q-9 Hydrolysis of ethyl acetate in acid base medium followed the order of reaction
(A) I & II Order
(B) Pseudo first & II Order
(C) II & I Order
(D) zero and first
Q-10 The rate of hydrolysis can be controlled by
(A) adding buffers
(B) complexation
(C) Removal of water
(D) decreasing the solubility
Q 11 Porosity of a porous powder is defined as
(A)Bulk volume/void volume
(B) void volume / Bulk volume
(C) void volume / true volume
(D) true volume / Bulk volume
Q-12 The HLB range of emulsifier used in the preparation of water in oil emulsion is
(A)4 to 6
(B) 7 to 12
(C) 13 to 15
(D) 16
Q-13 . Mannitol may be included in lyophilized products as a
(A) buffer
(B) bulking agent
(C) preservative
(D) sweetener
Q-14 Intrusion fluid found in Pychometer is
(A)Acetone
(B) Mercury
(C) Isopropyl alcohol
(D) Ethyl alcohol
Q-15 when cumulative percent frequency on a probability scale is plotted scale against logarithm
of the particle size, 50 % on the probability scale gives the powder particle diameter of
(A)arithmetic mean
(B) arithmetic mode
(C) geometric mean
(D)harmonic mean
Chemistry
Q-31 Dalteparin sodium acts in the body to
(A) regulate menstrual activity
(B) prevent blood clot formation
(C) inhibit thyroid function
(D) inhibit viral replication
Q-32 . Cromolyn sodium is a drug that is
(A) effective in acute asthmatic attacks
(B) a synthetic corticosteroid
(C) a histamine antagonist
(D) a mast cell stabilizer
Q-33. Which of the following calcium channel blockers may be employed parenterally in thetreatment of cardiac arrhythmias?
I. verapamil II. isradipine III. amlodipine
(A) I only
( B) III only
(C) I and II only
(D) II and III only
Q-35 . Which one of the following is NOT a progestin?
(A) norethynodrel
(B) norethindrone
(C) mestranol
(D) levonorgestrel
Q-36 . Potassium depletion is LEAST likely to occur in a patient using
(A) ethacrynic acid
(B) triamterene
(C) torsemide
(D) acetazolamide
Q-37. Which one of the following barbiturates is likely to be the shortest acting?
(A) amobarbital sodium
(B) methohexital sodium
(C) pentobarbital sodium
(D) mephobarbital
Q38. The primary function of simethicone in antacid products is to act as a (an)
(A) suspending agent
(B) adsorbent
(C) buffer
(D) antiflatulent
Q 39. The antiparkinson effect of levodopa may be inhibited by
(A) niacinamide
(B) d-alpha tocopherol
(C) pyridoxine HCl
(D) dihydrotachysterol
Q-40. The child’s dose of a drug is reported as 1.2 mg/kg body weight. What is the appropriate dose for a child weighing 60 lb?
(A) 6 mg
(B) 9 mg
(C) 32 mg
(D) 72 mg
Q-41. Calcium chloride (CaCl2 • 2H20) has a formula weight of 147. What weight of the chemical is needed to obtain 40 mEq of calcium? (Ca =40.1; Cl =35.5; H20 =18)
(A) 0.80 g
(B) 2.22 g
(C) 1.47 g
(D) 2.94 g
Q-42. The concentration of mercury in a water sample is reported as 5 ppm. Express this concentration as a percentage.
(A) 0.00005%
(B) 0.0005%
(C) 0.005%
(D) 0.05%
Q-45 Stereochemistry of penicillins is
(A)2S, 5R, 6R
(B) 2R, 5S, 6R
(C) 2R, 5S, 6S
(D)2S, 5S, 6R
Q-46 – Which one of the following chemicals is NOT suitable as a drug excipient?
(A) methyl paraben
(B) starch
(C) glycerin
(D) benzocaine
Q 47-A patient with sever viral hepatitis, will have increased plasma level of which of the following :
(A) Ck2
(B) LDH1
(C) hexokinase
(D) alanine transaminase
Q-50 In gas chromatography which detector is most sensitive to halogenated compounds like pesticides
(A) TCD
(B) FID
(C) ECD
(D) FP
Biology
Q.61 What is the correct region behind sickle cell anemia defect in HbS?
(A) Normally the 6th amino acid in the beta chain is glutamic acid, this is replaced by valine in the HbS molecule.
(B) Normally the 9th amino acid in the beta chain is glutamic acid, this is replaced by valine in the HbS molecule.
(C) Normally the 6th amino acid in the beta chain is glutamic acid, this is replaced by leucine in the HbS molecule.
(D) Normally the 6th amino acid in the beta chain is glutamic acid, this is replaced by isoleucine in the HbS molecule.
Q-62 (-) Hyoscyamine is
(A)15-20 times more active as a mydriatic than (+) Hyoscyamine
(B) inactive as a mydriatic
(C) 3-5 times less active as a mydriatic than (+) Hyoscyamine
(D)100 times more active as a mydriatic than (+) Hyoscyamine
Q- 63 The number of peaks given by the 1HNMR spectrum of 2-methyl-1-pentene is
(A)5
(B) 4
(C) 3
D. 6
Q-64 In HPLC, the analytical performance improves when
(A)Particle diameter is increased
(B) Particle diameter is decreased
(C) Coarser particles are paired with small column
(D) Low temperature is used
Q-65 M= (m2)2/ m1 here m2 is daughter ion & m1 is parent ion or molecular ion then M is
(A)Fragment ion
(B) Metastable ion
(C) Molecular Ion
(D) Rearrangement ion
Q-66 In per gram of powdered Lycopodium number of spores will be
(A) 94,000
(B) 94,000,000
(C) 94,000
(D) 94,000,000
Q-67 Halphen’s test is for the identification of
(A) Sesame oil
(B) Argemone oil
(C) Cotton seed oil
(D) Olive oil
Q-68 Microscopic characters of anticancer rhizome or roots of Podophyllum peltatum, Family Berberidaceae are
(A)In the rhizome eccentric pith is situated towards the upper surface & the vascular bundles are curved. The root exhibit a thick cork and central wood.
(B) Exhibit a varying number of concentric rings of fibrous vascular strands in which the phloem is towards the outer side and xylem is on the inner side.
(C) Cylindrical or sub cylindrical, flattened dorsiventrally. Shows a broken circle of vascular tissue with a distinct phloem.
(D)An erect, short, conical rhizome which may be longitudinally sliced, Shows a wellmarked, dark cambium line.