Name of the University : University of Mumbai
Name of the Exam : Ph.D Entrance Test
Subject: Bio Analytical Science
Document Type : Old Question Paper
Year : 2016
Website : https://mu.ac.in/
Download Model Question Paper : https://www.pdfquestion.in/uploads/14044-bioanalyticalscience.pdf
Bio Analytical Science Ph.D Entrance Test Question Paper
NB. (1) All questions are compulsory.
(2) Select the most appropriate answer from the alternatives provided for each of the following and write ONLY the correct option in your answer-book.
Related : University of Mumbai Ph.D Molecular Biology Entrance Test Question Paper : www.pdfquestion.in/14041.html
1) Extraction efficiency of a solute is best reflected by
a}Stabiiity of solute
b)Partition coefficient
c)pH of solvent
d)partial pressure
2)The route of administration that gives maximum bioavailability is»
a)|V
b)Orai
c)lM
d)SC
3)First pass effect refers to-
a)Liver metabolism
b)Gastric absorption
c)Enteric absorption
d)None of these
4)GCP guidelines for India are issued by-
a)DCGl
b)FDA
c)lCMR
d)Govt.Of Indi
5)Powder characteristics of crude plant drug is used in-
a)Pharmacognostic evaluation
b)Proximate analysis
c)l-lerbal analysis
d)None of these
6)Electronic signature is described in-
a)CFR 21 part 11
b)CFR 21 part 12
c)FDA guidelines
d) None of these
7)Sub family papilionaceae belongs to family-
a)Asteraceae
b)Leguminosae
c)Rosaceae
d)lVlaivaceae
8)Trichomes are found on-
a)ieaves –
b)roots
c)seeds
d)None of these
9)Extraction technique that relies on adsorption of solutes is-
a)liquid liquid extraction
b)SCFE
c)SPE
d)Soxhlet extraction
10)Arka Vati is a type of formulation in –
a)Ayurveda
b)Unani
c)Siddha
d)l—lomeopathy
11)Visualisation of bands after derivatizing a TLC plate can be done using-
a)Exposure to Safranine
b)Exposure to Nitrogen
c)Exposure to iodine crystals
d)none of these
12)Scanning of a TLC plate is based on the principle of-
a)Densitometry
b)Lambert’s law
c)Refractometry
d)Sonometry
13) Separation of solutes of similar nature by LC can be achieved by-
a)lsocratic HPLC
b)Gradient HPLC
c) GLC
d)LC-MS
14)Proteins are best separated in HPLC using-
a)ClB column
b)CQ column
c)Affinity column
d)lon exchange column
15)Enantiomers are separated in HPLC using-
a)chiral columns
b)phenyl column
c)affinity column
d) none of these
16. An example of a universal detector in LC is-
a)ELSD
b)UV detector
c)PDA detector
d)ECD
17)Active proteins are derived from their precursors by-
a)Protein folding
b)Determination
c)Post transnational modifications
d) none of these
18)The most characteristic feature of enzyme as a catalyst is its-
a)Specificity
b)non reactivity
c)stability d)none of these
19)Electroscopic separation is based on-
a)Ionic charge
b)pH
c)temperature
d)voltage
20)A technique that uses antibodies for detection is-
a)Electrophoresis
b)lsotachophoresis
c)ELlSA
d)none of these
21)The most influential international treaty that has changed lPR policies is-
a)TRIPS
b)CTES
c)WTO
d)Agenda 21
22)Stability studies helps us to predict-
a)Shelf life
b)Bio availability
c)APl degradation
d)none of these
23)The following type of formulation is the most influenced by food in the stomach-
a)intermediate release
b)Sustained release
c)injection
d)interment
24) DOLLY‘ was a-
a) Transgenic Sheep
b) Cloned sheep
c) Cloned Human embryo
d) none of these
25) The technique of ‘Test Tube Baby‘ can be described as ~
a) Artificial Insemination
b) in Vitro Fertilization
c) Surrogate Mother
d) Cloning
26. Each chromosome contains-
a) Double DNA molecule
b) Single DNA molecule
c) Diploid number of DNA molecules
d) Haploid number of DNA molecules
27) Albumins & globins can be precipitated in fractions from their solutions using-
a) HNOg
b) Ammonium Sulphate
c) CuSO4
d) Sodium Tungstate
28) Lipoproteins can be classified as –
a) Conjugated proteins
b) Derived proteins
c) Simpie proteins
d) none of these
29) Electrophoresis involves movement of ions in a matrix under-
a) Voltage gradient
b) Concentration Gradient
c) pH gradient
d) none of these
30) Major protein found in milk is-
a) Casein
b) Lactose
c) albumin
d) Collagen
31) A nucleoside consists of-
a) Base + sugar
b) base + phosphate
c) Phosphate + Sugar
d) none of these
32. RNA involved in translation during protein synthesis is –
a) t-RNA
b) r-RNA
c) m-RNA
d) none of these
33) Enzyme involved in DNA replication is-
a) DNA polymerase
b) DNA ligase
c) Transferase
d) RNA poiymerase