Organisation : Karunya University
Exam : End Semester Examination
Paper : Cancer Biology
Year : 2010
Document Type : Question Paper
Website : https://www.karunya.edu/
Download Model/Sample Question Paper : https://www.pdfquestion.in/uploads/10830-cancerbio.docx
Cancer Biology Model Question Paper :
Maximum marks : 100
Subject Code: 09BT253
Time: 3 hours
Related : Karunya University Entrance Exam Model Question Paper : www.pdfquestion.in/8816.html
Answer ALL questions :
PART – A : (10 x 1 = 10 MARKS)
1. Site any one of the molecular tools used in diagnosis of cancer.
2. Give any two tumor markers.
3. What are Oncogenes?
4. What is Apoptosis?
5. Mention the role of retroviruses in cancer.
6. What is a Malignant Tumor?
7. Define EGFR.
8. What is metastatic cascade?
9. Define the term “Colonization”.
10. Mention any two human carcinogens.
Part – B : (5 x 3 = 15 MARKS)
11. Discuss about different forms of cancer.
12. Differentiate between physical carcinogenesis and chemical carcinogenesis.
13. Write about Oncogenes activity.
14. Write short notes on membrane disruption.
15. Explain about gene therapy.
Part – C : (5 x 15 = 75 MARKS)
16. Explain in detail about on tumor surpressor genes.
(OR)
17. Discuss in detail about of mutation.
18. Discuss in detail about mechanisms of radiation carcinogenesis.
(OR)
19. Explain in detail about carcinogenesis.
20. a. Explain about functions of proto oncogene. (5)
b. Explain about growth factor receptor. (10)
(OR)
21. Give some example of oncogenes. Draw neatly the retrovirus life cycle and explain it.
22. Write briefly about proteinases and tumour cell invasion.
(OR)
23. Explain in detail about the clinical significance of invasion.
24. Write short notes on:
a. Chemotherapy (7)
b. Radiation Therapy (8)
(OR)
25. What are carcinogens? Explain the mechanism of radiation carcinogenesis.
Introductory Biotechnology :
Answer ALL questions :
Part – A : : (10 x 1 = 10 MARKS)
1. Define Biotechnology.
2. What is plant cell culture technology?
3. What is Cloning vector?
4. What is Cosmids?
5. What is Totipotency?
6. Which is the first cloned mammal?
7. What do you mean by symbiotic nitrogen fixation?
8. What is biofertilizers?
9. Define DNA library.
10. What is the significance of DNA finger printing?
PART – B : (5 x 3 = 15 MARKS)
11. Explain the achievements of biotechnology.
12. What is Expression vector? Mention its salient features and applications.
13. Write about the transgenic animals.
14. What are the different types of biofertilizers?
15. Explain the principle and applications of Biochips.
Part – C : (5 x 15 = 75 MARKS)
6. Explain the broad applications of DNA Profiling.
OR)
17. Describe the applications of biotechnology.
18. Explain the salient features and uses of PBR322, SV40 molecules.
(OR)
19. Write a detailed account on enzymes in gene cloning.
20. Explain the steps in the production of transgenic plants and add notes on herbicide and insect resistant transgenic plants.
(OR)
21. Discuss about the socio-economic issues of biotechnology.
22. Describe about the biological nitrogen fixation in plants.
(OR)
23. Explain about Integrated Nutrient supply and IPM system.
Fundamentals of Biological Systems :
Answer ALL questions :
Part – A : (10 x 1 = 10 MARKS)
1. Name the organelles that are part of the endomembrane system.
2. What is cell cycle?
3. Mention the role of hormones.
4. What is a second messenger?
5. Mention the different methods of staining of microbes.
6. Write the principle of electron microscopy.
7. What are micronutrients?
8. Name the types of culture media.
9. Define community.
10. Name the factors that influence biodiversity
Part – B : (5 x 3 = 15 MARKS)
11. Define Diffusion? What factors affect rate of diffusion?
12. What are neurotransmitters?
13. Write the taxonomic classification of organisms.
14. Explain briefly the TCA cycle.
15. Write the values of biodiversity.
Part – C : (5 x 15 = 75 MARKS)
16. Describe and contrast three methods of endocytosis with neat sketches.
(OR)
17. Discuss in detail about various phases of mitosis with neat sketches.
18. Explain in detail about G – protein receptor with example.
(OR)
19. Explain the role of CAMP and Inositol Phosphate as second messengers.
20. Explain briefly about any two types of light microscopy.
(OR)
21. Write short notes on :
a. Microbial Biosensors b. Nomenclature of microbes.
22. Briefly explain the phases of growth curve.
(OR)
23. Discuss in detail about aerobic bioenergetics.
24. Discuss briefly about uses of biodiversity and community biodiversity conservation.
(OR)
25. Write short notes on :
a. Access of genetic resources. b. Status of Biodiversity.